UniProt Q8N1Q1
Carbonic anhydrase 13 (Q8N1Q1)
Carbonic anhydrase 13 (UniProt Q8N1Q1), EC 4.2.1.1: 31 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N1Q1
- Protein
- Carbonic anhydrase 13
- EC
- 4.2.1.1
- Experimental structures
- 31
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 24 · 5 records with a druggable one
Structures
32 records of Q8N1Q1 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3CZV | Crystal structure of the human carbonic anhydrase XIII in complex with acetazolamide | x-ray diffraction | A, B | — | — |
| 3CZV | Crystal structure of the human carbonic anhydrase xiii in complex with acetazolamide | x-ray diffraction | A, B | — | — |
| 3D0N | Crystal structure of human carbonic anhydrase XIII | x-ray diffraction | A, B | — | — |
| 3D0N | Crystal structure of human carbonic anhydrase xiii | x-ray diffraction | A, B | — | — |
| 3DA2 | X-ray structure of human carbonic anhydrase 13 in complex with inhibitor | x-ray diffraction | A, B | — | — |
| 3DA2 | X-ray structure of human carbonic anhydrase 13 in complex with inhibitor | x-ray diffraction | A, B | — | — |
| 4HU1 | Crystal structure of human carbonic anhydrase isozyme XIII with the inhibitor. | x-ray diffraction | B, A | — | — |
| 4HU1 | Crystal structure of human carbonic anhydrase isozyme xiii with the inhibitor. | x-ray diffraction | B, A | — | — |
| 4KNM | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | A, B | — | — |
| 4KNM | Crystal structure of human carbonic anhydrase isozyme xiii with 2… | x-ray diffraction | A, B | — | — |
| 4KNN | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | B, A | — | — |
| 4KNN | Crystal structure of human carbonic anhydrase isozyme xiii with 2… | x-ray diffraction | B, A | — | — |
| 4QIZ | Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor | x-ray diffraction | A, B | — | — |
| 4QIZ | Crystal structure of human carbonic anhydrase isozyme xiii with inhibitor | x-ray diffraction | A, B | — | — |
| 4QJP | Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor | x-ray diffraction | B, A | — | — |
| 4QJP | Crystal structure of human carbonic anhydrase isozyme xiii with inhibitor | x-ray diffraction | B, A | — | — |
| 4QJX | Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor | x-ray diffraction | A | — | — |
| 4QJX | Crystal structure of human carbonic anhydrase isozyme xiii with inhibitor | x-ray diffraction | A | — | — |
| 4QSJ | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | B, A | — | — |
| 4QSJ | Crystal structure of human carbonic anhydrase isozyme xiii with 2… | x-ray diffraction | B, A | — | — |
| 5E2N | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | A, B | ZN, V14 | 5 (best 0.68) |
| 5E2N | Crystal structure of human carbonic anhydrase isozyme xiii with 3… | x-ray diffraction | A, B | — | — |
| 5LLA | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | B, A | ZN, 6YQ | 5 (best 0.70) |
| 5LLA | Crystal structure of human carbonic anhydrase isozyme xiii with 4-(1H… | x-ray diffraction | B, A | ZN, 6YQ | — |
| 5LLN | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | B, A | ZN, 3TV | 5 (best 0.70) |
| 5LLN | Crystal structure of human carbonic anhydrase isozyme xiii with 2,3,5… | x-ray diffraction | B, A | ZN, 3TV | — |
| 5OGJ | Crystal structure of human carbonic anhydrase isozyme xiii with 2… | x-ray diffraction | B, A | ZN, V90 | — |
| 5OHH | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | B, A | ZN, AZI, BCN, LCP, 5DU | 4 (best 0.69) |
| 5OHH | Crystal structure of human carbonic anhydrase isozyme xiii with 2… | x-ray diffraction | B, A | ZN, AZI, BCN, LCP, 5DU | — |
| 6G5U | Crystal structure of human carbonic anhydrase isozyme XIII with… | x-ray diffraction | B, A | ZN, ENN | 5 (best 0.76) |
| 6G5U | Crystal structure of human carbonic anhydrase isozyme xiii with N… | x-ray diffraction | B, A | ZN, ENN | — |
| Q8N1Q1 | AlphaFold monomer V2.0 prediction for carbonic anhydrase 13 (Q8N1Q1) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 10 records
- 3TV · 2,3,5,6-tetrafluoro-4-(propylsulfanyl) benzenesulfonamide · in 2 records
- 5DU · 2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide · in 2 records
- 6YQ · 4-[2-(benzimidazol-1-yl)ethanoyl]-2-chloranyl-benzenesulfonamide · in 2 records
- AZI · Azide ion · in 2 records
- BCN · Bicine · in 2 records
- ENN · ~{N}-butyl-2,4-bis(chloranyl)-5-sulfamoyl-benzamide · in 2 records
- LCP · Perchlorate ion · in 2 records
- V14 · 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide · in 1 record
- V90 · 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide · in 1 record
Experiment against prediction
- 3CZV chain B against the predicted model Q8N1Q1: TM-score 1.00, RMSD 0.43 Å
- 3CZV chain B against the predicted model Q8N1Q1: TM-score 1.00, RMSD 0.43 Å
- 4KNM chain A against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.43 Å
- 4KNM chain A against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.43 Å
- 6G5U chain B against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.45 Å
- 6G5U chain B against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.45 Å
- 3CZV chain A against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.46 Å
- 3CZV chain A against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.46 Å
- 3DA2 chain B against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.48 Å
- 3DA2 chain B against the predicted model Q8N1Q1: TM-score 0.99, RMSD 0.48 Å
Elsewhere
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