UniProt Q8KHZ8
Flavin-dependent tryptophan halogenase RebH (Q8KHZ8)
Flavin-dependent tryptophan halogenase RebH (UniProt Q8KHZ8), EC 1.14.19.9: 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 36 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8KHZ8
- Protein
- Flavin-dependent tryptophan halogenase RebH
- EC
- 1.14.19.9
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 36 · 4 records with a druggable one
Structures
19 records of Q8KHZ8 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E4G | RebH with bound L-Trp | x-ray diffraction | A, B | — | — |
| 2E4G | Rebh with bound L-TRP | x-ray diffraction | A, B | — | — |
| 2O9Z | Crystal Structure of RebH, a FAD-dependent halogenase from Lechevalieria aerocolonigenes, the Apo… | x-ray diffraction | A, B | — | — |
| 2O9Z | Crystal structure of rebh, a FAD-dependent halogenase from lechevalieria aerocolonigenes, the apo… | x-ray diffraction | A, B | — | — |
| 2OA1 | Crystal Structure of RebH, a FAD-dependent halogenase from Lechevalieria aerocolonigenes, the… | x-ray diffraction | A, B | — | — |
| 2OA1 | Crystal structure of rebh, a FAD-dependent halogenase from lechevalieria aerocolonigenes, the… | x-ray diffraction | A, B | — | — |
| 2OAL | RebH with bound FAD | x-ray diffraction | A, B | — | — |
| 2OAL | Rebh with bound FAD | x-ray diffraction | A, B | — | — |
| 2OAM | Apo RebH from Lechevalieria aerocolonigenes | x-ray diffraction | A, B | — | — |
| 2OAM | Apo rebh from lechevalieria aerocolonigenes | x-ray diffraction | A, B | — | — |
| 4LU6 | Thermostabilized RebH | x-ray diffraction | A, B | — | — |
| 4LU6 | Thermostabilized rebh | x-ray diffraction | A, B | — | — |
| 6P00 | RebH Variant 8F, Tryptamine 6-halogenase | x-ray diffraction | A, B | FAD | 9 (best 0.78) |
| 6P00 | Rebh variant 8F, tryptamine 6-halogenase | x-ray diffraction | A, B | FAD | — |
| 6P2V | RebH Variant 10S, Tryptamine 5-halogenase | x-ray diffraction | A, B | FAD | 7 (best 0.83) |
| 6P2V | Rebh variant 10S, tryptamine 5-halogenase | x-ray diffraction | A, B | FAD | — |
| 7JU0 | RebH Variant 0S, Tryptamine 7-halogenase with bound tryptamine | x-ray diffraction | A, B | FAD, TSS | 14 (best 0.80) |
| 7JU0 | Rebh variant 0S, tryptamine 7-halogenase with bound tryptamine | x-ray diffraction | A, B | FAD, TSS | — |
| Q8KHZ8 | AlphaFold monomer V2.0 prediction for flavin-dependent tryptophan halogenase rebh (Q8KHZ8) | predicted | A | — | 6 (best 0.78) |
Ligands
Experiment against prediction
- 2O9Z chain A against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.54 Å
- 2O9Z chain A against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.54 Å
- 6P2V chain B against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.54 Å
- 6P2V chain B against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.54 Å
- 7JU0 chain B against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.56 Å
- 7JU0 chain B against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.56 Å
- 2OAL chain B against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.58 Å
- 2OAL chain B against the predicted model Q8KHZ8: TM-score 1.00, RMSD 0.58 Å
- 2OA1 chain B against the predicted model Q8KHZ8: TM-score 0.99, RMSD 0.62 Å
- 2OA1 chain B against the predicted model Q8KHZ8: TM-score 0.99, RMSD 0.62 Å
Elsewhere
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