UniProt Q8IU57
Interferon lambda receptor 1 (Q8IU57)
Interferon lambda receptor 1 (UniProt Q8IU57): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IU57
- Protein
- Interferon lambda receptor 1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
9 records of Q8IU57 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IXD | Structure of human JAK1 FERM/SH2 in complex with IFN lambda receptor | x-ray diffraction | B | — | 1 (best 0.32) |
| 5IXD | Structure of human JAK1 FERM/SH2 in complex with ifn lambda receptor | x-ray diffraction | B | — | — |
| 5IXI | Structure of human JAK1 FERM/SH2 in complex with IFNLR1/IL10RA chimera | x-ray diffraction | B | — | 1 (best 0.31) |
| 5IXI | Structure of human JAK1 FERM/SH2 in complex with IFNLR1/IL10RA chimera | x-ray diffraction | B | — | — |
| 5L04 | Structure of interferon lambda 1 receptor with human kinase JAK1 | x-ray diffraction | B | — | 3 (best 0.61) |
| 5L04 | Structure of interferon lambda 1 receptor with human kinase JAK1 | x-ray diffraction | B | — | — |
| 5T5W | Structure of an affinity matured lambda-IFN/IFN-lambdaR1/IL-10Rbeta receptor complex | x-ray diffraction | B | NAG | 3 (best 0.71) |
| 5T5W | Structure of an affinity matured lambda-IFN/IFN-LAMBDAR1/IL-10RBETA receptor complex | x-ray diffraction | B | NAG | — |
| Q8IU57 | AlphaFold monomer V2.0 prediction for interferon lambda receptor 1 (Q8IU57) | predicted | A | — | 1 (best 0.36) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 5T5W chain B against the predicted model Q8IU57: TM-score 0.96, RMSD 1.05 Å
- 5T5W chain B against the predicted model Q8IU57: TM-score 0.96, RMSD 1.05 Å
- 5L04 chain B against the predicted model Q8IU57: TM-score 0.31, RMSD 3.21 Å
- 5L04 chain B against the predicted model Q8IU57: TM-score 0.31, RMSD 3.21 Å
- 5IXI chain B against the predicted model Q8IU57: TM-score 0.26, RMSD 2.93 Å
- 5IXI chain B against the predicted model Q8IU57: TM-score 0.26, RMSD 2.93 Å
- 5IXI chain B against the predicted model Q13651: TM-score 0.22, RMSD 2.85 Å
- 5IXI chain B against the predicted model Q13651: TM-score 0.22, RMSD 2.85 Å
- 5IXD chain B against the predicted model Q8IU57: TM-score 0.14, RMSD 2.69 Å
- 5IXD chain B against the predicted model Q8IU57: TM-score 0.14, RMSD 2.69 Å
Elsewhere
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