UniProt Q8IDJ8
Lysine--tRNA ligase (Q8IDJ8)
Lysine--tRNA ligase (UniProt Q8IDJ8), EC 6.1.1.6: 14 experimental structures on GenesisL1, 7 ligands bound, 42 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8IDJ8
- Protein
- Lysine--tRNA ligase
- EC
- 6.1.1.6
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 42 · 3 records with a druggable one
Structures
14 records of Q8IDJ8 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4H02 | Crystal structure of P. falciparum Lysyl-tRNA synthetase | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4H02 | Crystal structure of P. falciparum lysyl-tRNA synthetase | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4PG3 | Crystal structure of KRS complexed with inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 4PG3 | Crystal structure of krs complexed with inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 6HCU | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum bound to a difluoro… | x-ray diffraction | A, B | FYB | — |
| 6HCU | Crystal structure of lysyl-tRNA synthetase from plasmodium falciparum bound to a difluoro… | x-ray diffraction | A, B | FYB | — |
| 6HCV | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with a chromone… | x-ray diffraction | A, B | FYE | 10 (best 0.84) |
| 6HCV | Crystal structure of lysyl-tRNA synthetase from plasmodium falciparum complexed with a chromone… | x-ray diffraction | A, B | FYE | — |
| 6L3Y | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and… | x-ray diffraction | B, A | E5C, PO4 | — |
| 6L3Y | Crystal structure of lysyl-tRNA synthetase from plasmodium falciparum complexed with L-lysine and… | x-ray diffraction | B, A | E5C, PO4 | — |
| 6L4Q | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and… | x-ray diffraction | B, A | E5R, LYS | 12 (best 0.78) |
| 6L4Q | Crystal structure of lysyl-tRNA synthetase from plasmodium falciparum complexed with L-lysine and… | x-ray diffraction | B, A | E5R | — |
| 6M0T | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and… | x-ray diffraction | A, B, C, D | LYS, EZ3 | 20 (best 0.84) |
| 6M0T | Crystal structure of lysyl-tRNA synthetase from plasmodium falciparum complexed with L-lysine and… | x-ray diffraction | A, B, C, D | EZ3 | — |
Ligands
- E5C · (3R)-3-[[(3S)-3-ethylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one · in 2 records
- E5R · (3R)-3-[[(3R)-3-methylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one · in 2 records
- EZ3 · (3R)-3-[(R)-[(2R,6S)-6-methyloxan-2-yl]-oxidanyl-methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one · in 2 records
- FYB · ~{N}-[[4,4-bis(fluoranyl)-1-oxidanyl-cyclohexyl]methyl]-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide · in 2 records
- FYE · 6-fluoranyl-~{N}-[(1-oxidanylcyclohexyl)methyl]-4-oxidanylidene-chromene-2-carboxamide · in 2 records
- LYS · Lysine · in 2 records
- PO4 · Phosphate ion · in 2 records
Elsewhere
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