UniProt Q8CIB5
Fermitin family homolog 2 (Q8CIB5)
Fermitin family homolog 2 (UniProt Q8CIB5): 10 experimental structures and 1 predicted model on GenesisL1, 53 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8CIB5
- Protein
- Fermitin family homolog 2
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 53 · 6 records with a druggable one
Structures
11 records of Q8CIB5 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XPY | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A | — | 6 (best 0.77) |
| 5XPY | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A | — | — |
| 5XPZ | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A, B | — | 9 (best 0.76) |
| 5XPZ | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A, B | — | — |
| 5XQ0 | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A, B | — | 11 (best 0.79) |
| 5XQ0 | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A, B | — | — |
| 5XQ1 | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A, B | — | 9 (best 0.79) |
| 5XQ1 | Structural basis of kindlin-mediated integrin recognition and activation | x-ray diffraction | A, B | — | — |
| 8TEC | Crystal structure of Kindlin2 in complex with acylated beta1 integrin peptide | x-ray diffraction | A, B | — | 8 (best 0.74) |
| 8TEE | Crystal structure of Kindlin2 in complex with K794Q mutated beta1 integrin | x-ray diffraction | A, B | — | 10 (best 0.72) |
| Q8CIB5 | AlphaFold monomer V2.0 prediction for fermitin family homolog 2 (Q8CIB5) | predicted | A | — | — |
Experiment against prediction
- 5XPY chain A against the predicted model Q8CIB5: TM-score 0.94, RMSD 1.59 Å
- 5XPY chain A against the predicted model Q8CIB5: TM-score 0.94, RMSD 1.59 Å
- 5XPZ chain A against the predicted model Q8CIB5: TM-score 0.89, RMSD 1.64 Å
- 5XPZ chain A against the predicted model Q8CIB5: TM-score 0.89, RMSD 1.64 Å
- 8TEE chain A against the predicted model Q8CIB5: TM-score 0.88, RMSD 2.27 Å
- 8TEC chain B against the predicted model Q8CIB5: TM-score 0.88, RMSD 1.88 Å
- 5XPZ chain B against the predicted model Q8CIB5: TM-score 0.88, RMSD 1.67 Å
- 5XPZ chain B against the predicted model Q8CIB5: TM-score 0.88, RMSD 1.67 Å
- 8TEE chain B against the predicted model Q8CIB5: TM-score 0.87, RMSD 2.35 Å
- 5XQ1 chain B against the predicted model Q8CIB5: TM-score 0.86, RMSD 1.90 Å
Elsewhere
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