UniProt Q8C9A2
Endonuclease V (Q8C9A2)
Endonuclease V (UniProt Q8C9A2), EC 3.1.26.-: 22 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8C9A2
- Protein
- Endonuclease V
- EC
- 3.1.26.-
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 27 · 10 records with a druggable one
Structures
23 records of Q8C9A2 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5AOY | Structure of mouse Endonuclease V | x-ray diffraction | A | — | — |
| 5AOY | Structure of mouse endonuclease V | x-ray diffraction | A | — | — |
| 6OZJ | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | — | 2 (best 0.88) |
| 6OZJ | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | — | — |
| 6OZK | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | CA | 2 (best 0.86) |
| 6OZK | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | CA | — |
| 6OZL | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | MN, NA | 2 (best 0.80) |
| 6OZL | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | MN, NA | — |
| 6OZM | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | MN | 3 (best 0.86) |
| 6OZM | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | MN | — |
| 6OZN | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | MN | 4 (best 0.85) |
| 6OZN | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | MN | — |
| 6OZO | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | MN | 5 (best 0.86) |
| 6OZO | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | MN | — |
| 6OZP | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | MN | 3 (best 0.86) |
| 6OZP | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | MN | — |
| 6OZQ | Crystal structure of Mus musculus (Mm) Endonuclease V (K155M) in complex with a 23mer RNA oligo… | x-ray diffraction | A, B | MN | 2 (best 0.86) |
| 6OZQ | Crystal structure of mus musculus (mm) endonuclease V (K155M) in complex with a 23MER RNA oligo… | x-ray diffraction | A, B | MN | — |
| 6OZR | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | MG, K | 3 (best 0.86) |
| 6OZR | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | MG, K | — |
| 6OZS | Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing… | x-ray diffraction | A, B | MG, NA | 1 (best 0.87) |
| 6OZS | Crystal structure of mus musculus (mm) endonuclease V in complex with a 23MER RNA oligo containing… | x-ray diffraction | A, B | MG, NA | — |
| Q8C9A2 | AlphaFold monomer V2.0 prediction for endonuclease V (Q8C9A2) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6OZN chain B against the predicted model Q8C9A2: TM-score 0.98, RMSD 0.95 Å
- 6OZN chain B against the predicted model Q8C9A2: TM-score 0.98, RMSD 0.95 Å
- 6OZS chain B against the predicted model Q8C9A2: TM-score 0.98, RMSD 0.97 Å
- 6OZS chain B against the predicted model Q8C9A2: TM-score 0.98, RMSD 0.97 Å
- 6OZP chain B against the predicted model Q8C9A2: TM-score 0.97, RMSD 0.98 Å
- 6OZP chain B against the predicted model Q8C9A2: TM-score 0.97, RMSD 0.98 Å
- 6OZM chain B against the predicted model Q8C9A2: TM-score 0.97, RMSD 0.98 Å
- 6OZM chain B against the predicted model Q8C9A2: TM-score 0.97, RMSD 0.98 Å
- 6OZL chain B against the predicted model Q8C9A2: TM-score 0.97, RMSD 0.98 Å
- 6OZL chain B against the predicted model Q8C9A2: TM-score 0.97, RMSD 0.98 Å
Elsewhere
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