UniProt Q8C1E7
Ion channel TACAN (Q8C1E7)
Ion channel TACAN (UniProt Q8C1E7): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8C1E7
- Protein
- Ion channel TACAN
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 3 records with a druggable one
Structures
5 records of Q8C1E7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7N0K | Cryo-EM structure of TACAN in the apo form (TMEM120A) | electron microscopy | B, A | — | 6 (best 0.76) |
| 7N0K | Cryo-EM structure of tacan in the apo form (TMEM120A) | electron microscopy | B, A | — | — |
| 7N0L | Cryo-EM structure of TACAN in the H196A H197A mutant form (TMEM120A) | electron microscopy | A, B | COA | 5 (best 0.80) |
| 7N0L | Cryo-EM structure of tacan in the H196A H197A mutant form (TMEM120A) | electron microscopy | A, B | COA | — |
| Q8C1E7 | AlphaFold monomer V2.0 prediction for ion channel tacan (Q8C1E7) | predicted | A | — | 3 (best 0.76) |
Ligands
- COA · Coenzyme A · in 2 records
Experiment against prediction
- 7N0L chain B against the predicted model Q8C1E7: TM-score 0.87, RMSD 3.04 Å
- 7N0L chain A against the predicted model Q8C1E7: TM-score 0.87, RMSD 3.01 Å
- 7N0L chain A against the predicted model Q8C1E7: TM-score 0.87, RMSD 3.01 Å
- 7N0K chain B against the predicted model Q8C1E7: TM-score 0.86, RMSD 3.01 Å
- 7N0K chain B against the predicted model Q8C1E7: TM-score 0.86, RMSD 3.01 Å
Elsewhere
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