UniProt Q86YC2
Partner and localizer of BRCA2 (Q86YC2)
Partner and localizer of BRCA2 (UniProt Q86YC2): 6 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86YC2
- Protein
- Partner and localizer of BRCA2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
7 records of Q86YC2 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2W18 | Crystal structure of the C-terminal WD40 domain of human PALB2 | x-ray diffraction | A | — | — |
| 2W18 | Crystal structure of the C-terminal WD40 domain of human PALB2 | x-ray diffraction | A | — | — |
| 3EU7 | Crystal Structure of a PALB2 / BRCA2 complex | x-ray diffraction | A | — | — |
| 3EU7 | Crystal structure of a PALB2 / BRCA2 complex | x-ray diffraction | A | — | — |
| 7S4A | MRG15 complex with PALB2 peptide | x-ray diffraction | B, D | — | 4 (best 0.76) |
| 7S4A | MRG15 complex with PALB2 peptide | x-ray diffraction | B, D | — | — |
| Q86YC2 | AlphaFold monomer V2.0 prediction for partner and localizer of BRCA2 (Q86YC2) | predicted | A | — | 6 (best 0.79) |
Experiment against prediction
- 2W18 chain A against the predicted model Q86YC2: TM-score 0.99, RMSD 0.55 Å
- 2W18 chain A against the predicted model Q86YC2: TM-score 0.99, RMSD 0.55 Å
- 3EU7 chain A against the predicted model Q86YC2: TM-score 0.99, RMSD 0.66 Å
- 3EU7 chain A against the predicted model Q86YC2: TM-score 0.99, RMSD 0.66 Å
- 7S4A chain D against the predicted model Q86YC2: TM-score 0.43, RMSD 1.43 Å
- 7S4A chain D against the predicted model Q86YC2: TM-score 0.43, RMSD 1.43 Å
- 7S4A chain B against the predicted model Q86YC2: TM-score 0.38, RMSD 2.61 Å
- 7S4A chain B against the predicted model Q86YC2: TM-score 0.38, RMSD 2.61 Å
Elsewhere
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