UniProt Q86T24
Transcriptional regulator Kaiso (Q86T24)
Transcriptional regulator Kaiso (UniProt Q86T24): 29 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86T24
- Protein
- Transcriptional regulator Kaiso
- Experimental structures
- 29
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 13 · 3 records with a druggable one
Structures
30 records of Q86T24 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LT7 | Solution NMR structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site… | solution nmr | A | — | — |
| 2LT7 | Solution NMR structure of kaiso zinc finger DNA binding domain in complex with kaiso binding site… | solution nmr | A | — | — |
| 3FKC | Crystal Structure of Human Zinc finger and BTB domain containing 33 | x-ray diffraction | A | — | — |
| 3FKC | Crystal structure of human zinc finger and btb domain containing 33 | x-ray diffraction | A | — | — |
| 3M4T | Crystal structure of the BTB domain from Kaiso/ZBTB33, form I | x-ray diffraction | A | — | — |
| 3M4T | Crystal structure of the btb domain from KAISO/ZBTB33, form I | x-ray diffraction | A | — | — |
| 3M8V | Crystal structure of the BTB domain from Kaiso/ZBTB33, form II | x-ray diffraction | A | — | — |
| 3M8V | Crystal structure of the btb domain from KAISO/ZBTB33, form II | x-ray diffraction | A | — | — |
| 4F6M | Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA | x-ray diffraction | A | — | — |
| 4F6M | Crystal structure of kaiso zinc finger DNA binding domain in complex with kaiso binding site DNA | x-ray diffraction | A | — | — |
| 4F6N | Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA | x-ray diffraction | A | — | — |
| 4F6N | Crystal structure of kaiso zinc finger DNA binding protein in complex with methylated cpg site DNA | x-ray diffraction | A | — | — |
| 5VMU | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double cpg-methylated DNA… | x-ray diffraction | A | ZN, CL | — |
| 5VMV | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with its double cpg-methylated DNA… | x-ray diffraction | A | ZN, CL | — |
| 5VMW | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double cpg-methylated DNA… | x-ray diffraction | A | ZN, CL | — |
| 5VMX | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi cpg-methylated DNA resembling… | x-ray diffraction | A | ZN, CL | — |
| 5VMY | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling… | x-ray diffraction | A | ZN, CL | — |
| 5VMY | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi cpg-methylated DNA resembling… | x-ray diffraction | A | ZN, CL | — |
| 5VMZ | Kaiso (ZBTB33) E535Q mutant zinc finger DNA binding domain in complex with a double cpg-methylated… | x-ray diffraction | A | ZN, CL | — |
| 6DF5 | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific kaiso binding sequence… | x-ray diffraction | A | ZN, CL | — |
| 6DF8 | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence… | x-ray diffraction | A | ZN, CL | 5 (best 0.75) |
| 6DF8 | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific kaiso binding sequence… | x-ray diffraction | A | ZN, CL | — |
| 6DF9 | Kaiso (ZBTB33) E535Q zinc finger DNA binding domain in complex with the specific kaiso binding… | x-ray diffraction | A | ZN, CL | — |
| 6DFA | Kaiso (ZBTB33) E535A zinc finger DNA binding domain in complex with the specific kaiso binding… | x-ray diffraction | A | ZN, CL | — |
| 6DFB | Kaiso (ZBTB33) K539A zinc finger DNA binding domain in complex with the specific Kaiso binding… | x-ray diffraction | A | ZN, CL | 4 (best 0.82) |
| 6DFB | Kaiso (ZBTB33) K539A zinc finger DNA binding domain in complex with the specific kaiso binding… | x-ray diffraction | A | ZN, CL | — |
| 6DFC | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence… | x-ray diffraction | A | ZN, CL | 4 (best 0.71) |
| 6DFC | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific kaiso binding sequence… | x-ray diffraction | A | ZN, CL | — |
| 6V8U | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a modified kaiso binding sequence… | x-ray diffraction | A | ZN, CL | — |
| Q86T24 | AlphaFold monomer V2.0 prediction for transcriptional regulator kaiso (Q86T24) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3FKC chain A against the predicted model Q86T24: TM-score 0.99, RMSD 0.41 Å
- 3FKC chain A against the predicted model Q86T24: TM-score 0.99, RMSD 0.41 Å
- 6DF9 chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.52 Å
- 6DFA chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.55 Å
- 6DFB chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.58 Å
- 6DFB chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.58 Å
- 6DF8 chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.58 Å
- 6DF8 chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.58 Å
- 6V8U chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.61 Å
- 6DFC chain A against the predicted model Q86T24: TM-score 0.98, RMSD 0.59 Å
Elsewhere
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