UniProt Q818Z9

Phosphopentomutase (Q818Z9)

Phosphopentomutase (UniProt Q818Z9), EC 5.4.2.7: 40 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 111 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q818Z9
Protein: Phosphopentomutase
EC: 5.4.2.7
Experimental structures: 40
Predicted models: 1
Ligands: 4
Pockets: 111 · 20 records with a druggable one

Structures

41 records of Q818Z9 in the MolNFT archive: 40 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
3M8W	Phosphopentomutase from Bacillus cereus	x-ray diffraction	A, B, C	MN	5 (best 0.78)
3M8W	Phosphopentomutase from bacillus cereus	x-ray diffraction	A, B, C	—	—
3M8Y	Phosphopentomutase from Bacillus cereus after glucose-1,6-bisphosphate activation	x-ray diffraction	A, B, C	MN	6 (best 0.76)
3M8Y	Phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate activation	x-ray diffraction	A, B, C	—	—
3M8Z	Phosphopentomutase from Bacillus cereus bound with ribose-5-phosphate	x-ray diffraction	A, B, C	MN, HSX	5 (best 0.75)
3M8Z	Phosphopentomutase from bacillus cereus bound with ribose-5-phosphate	x-ray diffraction	A, B, C	—	—
3OT9	Phosphopentomutase from Bacillus cereus bound to glucose-1,6-bisphosphate	x-ray diffraction	A, B, C	MN, G16	6 (best 0.78)
3OT9	Phosphopentomutase from bacillus cereus bound to glucose-1,6- bisphosphate	x-ray diffraction	A, B, C	—	—
3TWZ	Phosphorylated Bacillus cereus phosphopentomutase in space group P212121	x-ray diffraction	A	MN	1 (best 0.65)
3TWZ	Phosphorylated bacillus cereus phosphopentomutase in space group P212121	x-ray diffraction	A	—	—
3TX0	Unphosphorylated Bacillus cereus phosphopentomutase in a P212121 crystal form	x-ray diffraction	A	MN	1 (best 0.66)
3TX0	Unphosphorylated bacillus cereus phosphopentomutase in a P212121 crystal form	x-ray diffraction	A	—	—
3UN2	Phosphopentomutase T85Q variant enzyme	x-ray diffraction	A, B, C	MN	5 (best 0.78)
3UN2	Phosphopentomutase T85Q variant enzyme	x-ray diffraction	A, B, C	—	—
3UN3	phosphopentomutase T85Q variant soaked with glucose 1,6-bisphosphate	x-ray diffraction	A, B, C	MN, G16	6 (best 0.78)
3UN3	Phosphopentomutase T85Q variant soaked with glucose 1,6-bisphosphate	x-ray diffraction	A, B, C	—	—
3UN5	Bacillus cereus phosphopentomutase T85E variant	x-ray diffraction	A, B, C, D, E, F	MN	13 (best 0.76)
3UN5	Bacillus cereus phosphopentomutase T85E variant	x-ray diffraction	A, B, C, D, E, F	—	—
3UNY	Bacillus cereus phosphopentomutase T85E variant soaked with glucose 1,6-bisphosphate	x-ray diffraction	A, B, C, D, E, F	MN	11 (best 0.76)
3UNY	Bacillus cereus phosphopentomutase T85E variant soaked with glucose 1, 6-bisphosphate	x-ray diffraction	A, B, C, D, E, F	—	—
3UO0	phosphorylated Bacillus cereus phosphopentomutase soaked with glucose 1,6-bisphosphate	x-ray diffraction	A, B, C	MN, G16	6 (best 0.76)
3UO0	Phosphorylated bacillus cereus phosphopentomutase soaked with glucose 1,6-bisphosphate	x-ray diffraction	A, B, C	—	—
4LR7	Phosphopentomutase S154A variant	x-ray diffraction	A, B, C	MN	6 (best 0.80)
4LR7	Phosphopentomutase S154A variant	x-ray diffraction	A, B, C	—	—
4LR8	Phosphopentomutase S154A variant soaked with ribose 5-phosphate	x-ray diffraction	A, B, C	MN, HSX	7 (best 0.74)
4LR8	Phosphopentomutase S154A variant soaked with ribose 5-phosphate	x-ray diffraction	A, B, C	—	—
4LR9	Phosphopentomutase S154A variant soaked with 2,3-dideoxyribose 5-phosphate	x-ray diffraction	A, B, C	MN, 1X4	6 (best 0.77)
4LR9	Phosphopentomutase S154A variant soaked with 2,3-dideoxyribose 5- phosphate	x-ray diffraction	A, B, C	—	—
4LRA	Phosphopentomutase S154G variant	x-ray diffraction	A, B, C	MN	5 (best 0.78)
4LRA	Phosphopentomutase S154G variant	x-ray diffraction	A, B, C	—	—
4LRB	Phosphopentomutase S154G variant soaked with 2,3-dideoxyribose 5-phosphate	x-ray diffraction	A, B, C	MN, 1X4	5 (best 0.78)
4LRB	Phosphopentomutase S154G variant soaked with 2,3-dideoxyribose 5- phosphate	x-ray diffraction	A, B, C	—	—
4LRC	Phosphopentomutase V158L variant	x-ray diffraction	A, B, C	MN	5 (best 0.78)
4LRC	Phosphopentomutase V158L variant	x-ray diffraction	A, B, C	—	—
4LRD	Phosphopentomutase 4H11 variant	x-ray diffraction	A	MN	2 (best 0.65)
4LRD	Phosphopentomutase 4H11 variant	x-ray diffraction	A	—	—
4LRE	Phosphopentomutase soaked with 2,3-dideoxyribose 5-phosphate	x-ray diffraction	A, B, C	MN, 1X4	4 (best 0.78)
4LRE	Phosphopentomutase soaked with 2,3-dideoxyribose 5-phosphate	x-ray diffraction	A, B, C	—	—
4LRF	Phosphopentomutase S154G variant soaked with ribose 5-phosphate	x-ray diffraction	A, B, C	MN, HSX	6 (best 0.77)
4LRF	Phosphopentomutase S154G variant soaked with ribose 5-phosphate	x-ray diffraction	A, B, C	—	—
Q818Z9	AlphaFold monomer V2.0 prediction for phosphopentomutase (Q818Z9)	predicted	A	—	—

Ligands

MN · Manganese (II) ion · in 20 records
1X4 · 2,3-dideoxy-5-O-phosphono-alpha-D-ribofuranose · in 3 records
G16 · 1,6-di-O-phosphono-alpha-D-glucopyranose · in 3 records
HSX · 5-O-phosphono-alpha-D-ribofuranose · in 3 records

Experiment against prediction

4LRB chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.47 Å
4LRB chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.47 Å
4LRA chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.47 Å
4LRA chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.47 Å
4LRF chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.49 Å
4LRF chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.49 Å
4LR8 chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.49 Å
4LR8 chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.49 Å
3M8Z chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.50 Å
3M8Z chain A against the predicted model Q818Z9: TM-score 1.00, RMSD 0.50 Å

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.