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UniProt Q7ZWC3

Nudix (Nucleoside diphosphate linked moiety X)-type motif 1 (Q7ZWC3)

Nudix (Nucleoside diphosphate linked moiety X)-type motif 1 (UniProt Q7ZWC3): 4 experimental structures on GenesisL1, 5 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q7ZWC3
Protein
Nudix (Nucleoside diphosphate linked moiety X)-type motif 1
Experimental structures
4
Predicted models
0
Ligands
5
Pockets
1 · 1 record with a druggable one

Structures

4 records of Q7ZWC3 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5HZXCrystal structure of zebrafish MTH1 in complex with TH588x-ray diffractionA, B2GE, SO4—
5HZXCrystal structure of zebrafish MTH1 in complex with TH588x-ray diffractionA, B——
5OTNCrystal structure of zebrafish MTH1 in complex with O6-methyl-dGMPx-ray diffractionA6OG, CA, CL1 (best 0.72)
5OTNCrystal structure of zebrafish MTH1 in complex with O6-methyl-dgmpx-ray diffractionA6OG, CA, CL—

Ligands

  • 6OG · 6-O-methyl guanosine-5'-monophosphate · in 2 records
  • CA · Calcium ion · in 2 records
  • CL · Chloride ion · in 2 records
  • 2GE · N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine · in 1 record
  • SO4 · Sulfate ion · in 1 record

Elsewhere

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