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Ligand · 6OG

6OG · 6-O-methyl guanosine-5'-monophosphate

6OG, 6-O-methyl guanosine-5'-monophosphate (C11 H16 N5 O7 P, 361.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
6OG
Formula
C11 H16 N5 O7 P
Class
ligand
Structures
4
PDB entries
2

Binding sites

6OG in 4 structures; the first of them:

  • 5OTM · Crystal structure of human MTH1 in complex with O6-methyl-dGMP · 6OG A206 · binds TYR7, THR8, LEU9, LYS23, PHE27, ASN33, PHE35, GLY36 and 12 more
  • 5OTN · Crystal structure of zebrafish MTH1 in complex with O6-methyl-dGMP · 6OG A201 · binds LEU7, THR8, LEU9, LYS23, PHE27, ASN33, PHE35, GLY36 and 11 more
  • 5OTM · Crystal structure of human MTH1 in complex with O6-methyl-dgmp · 6OG A206 · binds TYR7, THR8, LEU9, LYS23, PHE27, ASN33, GLY36, GLY37 and 9 more
  • 5OTN · Crystal structure of zebrafish MTH1 in complex with O6-methyl-dgmp · 6OG A201 · binds THR8, LEU9, LYS23, PHE27, ASN33, GLY36, GLY37, LYS38 and 7 more

Residues it binds most

PHE 6, ASP 6, GLY 6, LYS 6, TRP 6, LEU 6, ASN 6, MET 6, THR 6, GLU 5 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • CL · Chloride ion
  • SO4 · Sulfate ion
  • ACT · Acetate ion
  • EDO · 1,2-ethanediol
  • GOL · Glycerol

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