UniProt Q7CRA4
Penicillin-binding protein 1b (Q7CRA4)
Penicillin-binding protein 1b (UniProt Q7CRA4), EC 2.3.2.-, 2.4.1.129: 31 experimental structures on GenesisL1, 4 ligands bound, 11 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7CRA4
- Protein
- Penicillin-binding protein 1b
- EC
- 2.3.2.-, 2.4.1.129
- Experimental structures
- 31
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 11 · 2 records with a druggable one
Structures
31 records of Q7CRA4 in the MolNFT archive: 31 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2UWX | Active site restructuring regulates ligand recognition in class A penicillin-binding proteins | x-ray diffraction | A | — | — |
| 2UWX | Active site restructuring regulates ligand recognition in class a penicillin-binding proteins | x-ray diffraction | A | — | — |
| 2XD1 | Active site restructuring regulates ligand recognition in class a penicillin-binding proteins | x-ray diffraction | A, B | — | — |
| 2XD1 | Active site restructuring regulates ligand recognition in class a penicillin-binding proteins | x-ray diffraction | A, B | — | — |
| 2XD5 | Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b | x-ray diffraction | A, B | — | — |
| 2XD5 | Structural insights into the catalytic mechanism and the role of streptococcus pneumoniae PBP1B | x-ray diffraction | A, B | — | — |
| 2Y2G | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (A01) | x-ray diffraction | A, B | — | — |
| 2Y2G | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (A01) | x-ray diffraction | A, B | — | — |
| 2Y2H | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA2) | x-ray diffraction | A, B | — | — |
| 2Y2H | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA2) | x-ray diffraction | A, B | — | — |
| 2Y2I | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA3) | x-ray diffraction | A | — | — |
| 2Y2I | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA3) | x-ray diffraction | A | — | — |
| 2Y2J | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA4) | x-ray diffraction | A | — | — |
| 2Y2J | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA4) | x-ray diffraction | A | — | — |
| 2Y2K | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA5) | x-ray diffraction | A | — | — |
| 2Y2K | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA5) | x-ray diffraction | A | — | — |
| 2Y2L | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (E06) | x-ray diffraction | A, B | — | — |
| 2Y2L | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (E06) | x-ray diffraction | A, B | — | — |
| 2Y2M | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (E08) | x-ray diffraction | A | — | — |
| 2Y2M | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (E08) | x-ray diffraction | A | — | — |
| 2Y2N | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (E07) | x-ray diffraction | A | — | — |
| 2Y2N | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (E07) | x-ray diffraction | A | — | — |
| 2Y2O | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (EO9) | x-ray diffraction | A | — | — |
| 2Y2O | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (EO9) | x-ray diffraction | A | — | — |
| 2Y2P | Penicillin-binding protein 1b (pbp-1b) in complex with an alkyl boronate (z10) | x-ray diffraction | A | — | — |
| 2Y2P | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (Z10) | x-ray diffraction | A | — | — |
| 2Y2Q | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (Z06) | x-ray diffraction | A, B | — | — |
| 2Y2Q | Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (Z06) | x-ray diffraction | A, B | — | — |
| 7ZUH | PENICILLIN-BINDING PROTEIN 1B (PBP-1B) Streptococcus pneumoniae R6 | x-ray diffraction | AAA | MG, CL | 4 (best 0.47) |
| 7ZUJ | PENICILLIN-BINDING PROTEIN 1B (PBP-1B) in complex with lactone 6Az - Streptococcus pneumoniae R6 | x-ray diffraction | AAA | KQN, CL | 4 (best 0.55) |
| 7ZUK | PENICILLIN-BINDING PROTEIN 1B (PBP-1B) in complex with lactone 7Az - Streptococcus pneumoniae R6 | x-ray diffraction | AAA | KQI, CL | 3 (best 0.56) |
Ligands
- CL · Chloride ion · in 3 records
- KQI · 6-azido-N-[(2S)-1-oxidanylidene-1-[[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]amino]-3-phenyl-propan-2-yl]hexanamide · in 1 record
- KQN · 6-azido-N-[(2S)-1-oxidanylidene-1-[[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]amino]propan-2-yl]hexanamide · in 1 record
- MG · Magnesium ion · in 1 record
Elsewhere
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