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Ligand · ZA4

ZA4 · [(2-fluorophenyl)carbonylamino]methyl-trihydroxy-boron

ZA4, [(2-fluorophenyl)carbonylamino]methyl-trihydroxy-boron (C8 H10 B F N O4 -1, 214.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
ZA4
Formula
C8 H10 B F N O4 -1
Class
ligand
Structures
2
PDB entries
1

Binding sites

ZA4 in 2 structures; the first of them:

  • 2Y2J · Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA4) · ZA4 A1000 · binds SER457, ALA459, SER460, LYS463, TYR498, SER516, ASN518, SER553 and 7 more
  • 2Y2J · Penicillin-binding protein 1B (pbp-1B) in complex with an alkyl boronate (ZA4) · ZA4 A1000 · binds SER457, ALA459, SER460, LYS463, TYR498, SER516, ASN518, SER553 and 7 more

Residues it binds most

GLY 2, SER 2, THR 2, ALA 2, ASN 2, LYS 2, MET 2, TYR 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • CL · Chloride ion
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

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