UniProt Q712K3
Ubiquitin-conjugating enzyme E2 R2 (Q712K3)
Ubiquitin-conjugating enzyme E2 R2 (UniProt Q712K3), EC 2.3.2.23: 5 experimental structures on GenesisL1, 4 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q712K3
- Protein
- Ubiquitin-conjugating enzyme E2 R2
- EC
- 2.3.2.23
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 16 · 3 records with a druggable one
Structures
5 records of Q712K3 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NYO | Crystal structure of a human Cdc34-ubiquitin thioester mimetic | x-ray diffraction | A | U94, PO4 | 5 (best 0.62) |
| 6NYO | Crystal structure of a human CDC34-ubiquitin thioester mimetic | x-ray diffraction | A | U94, PO4 | — |
| 8Q7R | Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C… | electron microscopy | C | U9O | 4 (best 0.79) |
| 8R5H | Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34… | electron microscopy | C | SY8 | 7 (best 0.82) |
| Q712K3 | AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2 R2 (Q712K3) | — | — | — |
Ligands
Elsewhere
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