UniProt Q6ZJK7
Tryptophan decarboxylase 1 (Q6ZJK7)
Tryptophan decarboxylase 1 (UniProt Q6ZJK7), EC 4.1.1.-: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6ZJK7
- Protein
- Tryptophan decarboxylase 1
- EC
- 4.1.1.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 16 · 1 record with a druggable one
Structures
7 records of Q6ZJK7 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6KHN | Crystal structure of Oryza sativa TDC with PLP and SEROTONIN | x-ray diffraction | A, B | PLP, SRO, CA | 11 (best 0.81) |
| 6KHN | Crystal structure of oryza sativa tdc with plp and serotonin | x-ray diffraction | A, B | PLP, SRO, CA | — |
| 6KHO | Crystal structure of Oryza sativa TDC with PLP | x-ray diffraction | A, B | PLP, CA | — |
| 6KHO | Crystal structure of oryza sativa tdc with plp | x-ray diffraction | A, B | PLP, CA | — |
| 6KHP | Crystal structure of Oryza sativa TDC with PLP and tryptamine | x-ray diffraction | A, B | PLP, TSS, CA | — |
| 6KHP | Crystal structure of oryza sativa tdc with plp and tryptamine | x-ray diffraction | A, B | PLP, TSS, CA | — |
| Q6ZJK7 | AlphaFold monomer V2.0 prediction for tryptophan decarboxylase 1 (Q6ZJK7) | predicted | A | — | 5 (best 0.47) |
Ligands
Experiment against prediction
- 6KHP chain A against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.73 Å
- 6KHP chain A against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.73 Å
- 6KHN chain A against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.74 Å
- 6KHN chain A against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.74 Å
- 6KHO chain A against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.77 Å
- 6KHO chain A against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.77 Å
- 6KHO chain B against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.94 Å
- 6KHO chain B against the predicted model Q6ZJK7: TM-score 0.99, RMSD 0.94 Å
- 6KHP chain B against the predicted model Q6ZJK7: TM-score 0.99, RMSD 1.01 Å
- 6KHP chain B against the predicted model Q6ZJK7: TM-score 0.99, RMSD 1.01 Å
Elsewhere
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