UniProt Q6UWV6
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (Q6UWV6)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (UniProt Q6UWV6), EC 3.1.4.12: 3 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 1 pocket. Binding sites, druggability and experiment…
- UniProt
- Q6UWV6
- Protein
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
- EC
- 3.1.4.12
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 1 · 1 record with a druggable one
Structures
4 records of Q6UWV6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TCD | Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine | x-ray diffraction | A | NAG, FUC, ZN, NA, IOD, PC | 1 (best 0.54) |
| 5TCD | Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine | x-ray diffraction | A | NAG, FUC, ZN, NA, IOD, PC | — |
| 5UDY | Human alkaline sphingomyelinase (ALK-smase, ENPP7, NPP7) | x-ray diffraction | A | NAG, FUC, ZN, NA, IOD | — |
| Q6UWV6 | AlphaFold monomer V2.0 prediction for ectonucleotide PYROPHOSPHATASE/PHOSPHODIESTERASE family… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5UDY chain A against the predicted model Q6UWV6: TM-score 1.00, RMSD 0.18 Å
- 5TCD chain A against the predicted model Q6UWV6: TM-score 1.00, RMSD 0.18 Å
- 5TCD chain A against the predicted model Q6UWV6: TM-score 1.00, RMSD 0.18 Å
Elsewhere
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