UniProt Q6P587
Acylpyruvase FAHD1, mitochondrial (Q6P587)
Acylpyruvase FAHD1, mitochondrial (UniProt Q6P587), EC 3.7.1.5, 4.1.1.3: 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q6P587
- Protein
- Acylpyruvase FAHD1, mitochondrial
- EC
- 3.7.1.5, 4.1.1.3
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 1 record with a druggable one
Structures
6 records of Q6P587 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SAW | X-ray structure of homo sapiens protein FLJ36880 | x-ray diffraction | A, B | — | — |
| 1SAW | X-ray structure of homo sapiens protein FLJ36880 | x-ray diffraction | A, B | — | — |
| 6FOG | X-ray structure of homo sapiens Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1)… | x-ray diffraction | A, G, F, D, B, C, H, E | MG, OXL, CL | 20 (best 0.79) |
| 6FOG | X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1)… | x-ray diffraction | A, G, F, D, B, C, H, E | MG, OXL, CL | — |
| 6FOH | X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1)… | x-ray diffraction | A, B | CL, MG | — |
| Q6P587 | AlphaFold monomer V2.0 prediction for acylpyruvase FAHD1, mitochondrial (Q6P587) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6FOG chain E against the predicted model Q6P587: TM-score 1.00, RMSD 0.37 Å
- 6FOG chain E against the predicted model Q6P587: TM-score 1.00, RMSD 0.37 Å
- 6FOG chain B against the predicted model Q6P587: TM-score 0.99, RMSD 0.43 Å
- 6FOG chain B against the predicted model Q6P587: TM-score 0.99, RMSD 0.43 Å
- 6FOG chain G against the predicted model Q6P587: TM-score 0.99, RMSD 0.43 Å
- 6FOG chain G against the predicted model Q6P587: TM-score 0.99, RMSD 0.43 Å
- 6FOG chain H against the predicted model Q6P587: TM-score 0.99, RMSD 0.46 Å
- 6FOG chain H against the predicted model Q6P587: TM-score 0.99, RMSD 0.46 Å
- 6FOG chain D against the predicted model Q6P587: TM-score 0.99, RMSD 0.46 Å
- 6FOG chain D against the predicted model Q6P587: TM-score 0.99, RMSD 0.46 Å
Elsewhere
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