UniProt Q6NAM1
Fluoroacetate dehalogenase (Q6NAM1)
Fluoroacetate dehalogenase (UniProt Q6NAM1), EC 3.8.1.3: 83 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6NAM1
- Protein
- Fluoroacetate dehalogenase
- EC
- 3.8.1.3
- Experimental structures
- 83
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 44 · 7 records with a druggable one
Structures
84 records of Q6NAM1 in the MolNFT archive: 83 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3R3U | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/apo | x-ray diffraction | A, B, C, D | — | — |
| 3R3U | Crystal structure of the fluoroacetate dehalogenase RPA1163 - WT/APO | x-ray diffraction | A, B, C, D | — | — |
| 3R3V | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Fluoroacetate | x-ray diffraction | A, B | — | — |
| 3R3V | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN/FLUOROACETATE | x-ray diffraction | A, B | — | — |
| 3R3W | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate | x-ray diffraction | A, B | — | — |
| 3R3W | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN/CHLOROACETATE | x-ray diffraction | A, B | — | — |
| 3R3X | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Bromoacetate | x-ray diffraction | A, B | — | — |
| 3R3X | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN/BROMOACETATE | x-ray diffraction | A, B | — | — |
| 3R3Y | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate | x-ray diffraction | A, B | — | — |
| 3R3Y | Crystal structure of the fluoroacetate dehalogenase RPA1163 - HIS280ASN/FLUOROACETATE | x-ray diffraction | A, B | — | — |
| 3R3Z | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/Glycolate | x-ray diffraction | A, B, C, D | — | — |
| 3R3Z | Crystal structure of the fluoroacetate dehalogenase RPA1163 - WT/GLYCOLATE | x-ray diffraction | A, B, C, D | — | — |
| 3R40 | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/apo | x-ray diffraction | A, B | — | — |
| 3R40 | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN/APO | x-ray diffraction | A, B | — | — |
| 3R41 | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/apo | x-ray diffraction | A, B | — | — |
| 3R41 | Crystal structure of the fluoroacetate dehalogenase RPA1163 - HIS280ASN/APO | x-ray diffraction | A, B | — | — |
| 5K3A | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate… | x-ray diffraction | A, B | CL | 2 (best 0.57) |
| 5K3A | Crystal structure of the fluoroacetate dehalogenase RPA1163 - HIS280ASN/FLUOROACETATE… | x-ray diffraction | A, B | CL | — |
| 5K3B | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate… | x-ray diffraction | A, B | CL, R3W | 2 (best 0.47) |
| 5K3B | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN/CHLOROACETATE… | x-ray diffraction | A, B | CL, R3W | — |
| 5K3C | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/5-Fluorotryptophan | x-ray diffraction | A, B | CL | — |
| 5K3C | Crystal structure of the fluoroacetate dehalogenase RPA1163 - WT/5- fluorotryptophan | x-ray diffraction | A, B | CL | — |
| 5K3D | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/Apo - No Halide | x-ray diffraction | A, B | — | 2 (best 0.64) |
| 5K3D | Crystal structure of the fluoroacetate dehalogenase RPA1163 - WT/APO - no halide | x-ray diffraction | A, B | — | — |
| 5K3E | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Glycolate - Cocrystallized | x-ray diffraction | A, B | GOA, CL | — |
| 5K3E | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN/GLYCOLATE - cocrystallized | x-ray diffraction | A, B | GOA, CL | — |
| 5K3F | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate… | x-ray diffraction | A, B | CL | 2 (best 0.60) |
| 5K3F | Crystal structure of the fluoroacetate dehalogenase RPA1163 - HIS280ASN/FLUOROACETATE… | x-ray diffraction | A, B | CL | — |
| 5NYV | Crystal structure determination from picosecond infrared laser ablated protein crystals by serial… | x-ray diffraction | A, B | — | 2 (best 0.44) |
| 5NYV | Crystal structure determination from picosecond infrared laser ablated protein crystals by serial… | x-ray diffraction | A, B | — | — |
| 5O2G | Crystal structure determination from picosecond infrared laser ablated protein crystals by serial… | x-ray diffraction | A, B | — | 3 (best 0.52) |
| 5O2G | Crystal structure determination from picosecond infrared laser ablated protein crystals by serial… | x-ray diffraction | A, B | — | — |
| 5O2I | An efficient setup for fixed-target, time-resolved serial crystallography with optical excitation | x-ray diffraction | A, B | — | 2 (best 0.42) |
| 5O2I | An efficient setup for fixed-target, time-resolved serial crystallography with optical excitation | x-ray diffraction | A, B | — | — |
| 5SWN | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Fluoroacetate… | x-ray diffraction | A, B | FAH, CL | 2 (best 0.45) |
| 5SWN | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN/FLUOROACETATE… | x-ray diffraction | A, B | FAH, CL | — |
| 5T4T | Crystal structure of the fluoroacetate dehalogenase RPA1163 - ASP110ASN - apo no halide | x-ray diffraction | B, A | — | — |
| 6FSX | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography | x-ray diffraction | A, B | — | — |
| 6FSX | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography | x-ray diffraction | A, B | — | — |
| 6GXD | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | FAH, CL | — |
| 6GXD | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | FAH, CL | — |
| 6GXF | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | — | — |
| 6GXF | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | — | — |
| 6GXH | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: FAcD… | x-ray diffraction | A, B | — | — |
| 6GXH | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: facd… | x-ray diffraction | A, B | — | — |
| 6GXL | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | — | — |
| 6GXL | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | — | — |
| 6GXT | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | FAH | — |
| 6GXT | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography… | x-ray diffraction | A, B | FAH | — |
| 6MUH | Fluoroacetate dehalogenase, room temperature structure solved by serial 1 degree oscillation… | x-ray diffraction | A, B | — | 2 (best 0.41) |
| 6MUH | Fluoroacetate dehalogenase, room temperature structure solved by serial 1 degree oscillation… | x-ray diffraction | A, B | — | — |
| 6MUY | Fluoroacetate dehalogenase, room temperature structure solved by serial 3 degree oscillation… | x-ray diffraction | A, B | CA | 2 (best 0.43) |
| 6MUY | Fluoroacetate dehalogenase, room temperature structure solved by serial 3 degree oscillation… | x-ray diffraction | A, B | CA | — |
| 6MZZ | Fluoroacetate dehalogenase, room temperature structure, using first 1 degree of total 3 degree… | x-ray diffraction | A, B | CA | — |
| 6N00 | Fluoroacetate dehalogenase, room temperature structure, using last 1 degree of total 3 degree… | x-ray diffraction | A, B | CA | — |
| 6N00 | Fluoroacetate dehalogenase, room temperature structure, using last 1 degree of total 3 degree… | x-ray diffraction | A, B | CA | — |
| 6QHP | Time resolved structural analysis of the full turnover of an enzyme - 2256 ms covalent intermediate… | x-ray diffraction | A, B | FAH | 2 (best 0.41) |
| 6QHP | Time resolved structural analysis of the full turnover of an enzyme - 2256 ms covalent intermediate… | x-ray diffraction | A, B | FAH | — |
| 6QHQ | Time resolved structural analysis of the full turnover of an enzyme - 1128 ms | x-ray diffraction | A, B | FAH | — |
| 6QHS | Time resolved structural analysis of the full turnover of an enzyme - 564 ms | x-ray diffraction | A, B | FAH | 2 (best 0.39) |
24 records more on the page itself.
Ligands
Experiment against prediction
- 5SWN chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.17 Å
- 5SWN chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.17 Å
- 5T4T chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.18 Å
- 3R40 chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.18 Å
- 3R40 chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.18 Å
- 5K3D chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.18 Å
- 5K3D chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.18 Å
- 3R3V chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.18 Å
- 3R3V chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.18 Å
- 3R3W chain B against the predicted model Q6NAM1: TM-score 1.00, RMSD 0.19 Å
Elsewhere
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