UniProt Q6FI13
Histone H2A type 2-A (Q6FI13)
Histone H2A type 2-A (UniProt Q6FI13): 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 69 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6FI13
- Protein
- Histone H2A type 2-A
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 69 · 6 records with a druggable one
Structures
16 records of Q6FI13 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SE0 | Class 1 : CENP-A nucleosome | electron microscopy | C, G | — | 12 (best 0.80) |
| 6SE0 | Class 1 : cenp-a nucleosome | electron microscopy | C, G | — | — |
| 6SE6 | Class2 : CENP-A nucleosome in complex with CENP-C central region | electron microscopy | C, G | — | — |
| 6SE6 | CLASS2 : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | C, G | — | — |
| 6SEE | Class2A : CENP-A nucleosome in complex with CENP-C central region | electron microscopy | C, G | — | 12 (best 0.85) |
| 6SEE | CLASS2A : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | C, G | — | — |
| 6SEF | Class2C : CENP-A nucleosome in complex with CENP-C central region | electron microscopy | C, G | — | 11 (best 0.81) |
| 6SEF | CLASS2C : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | C, G | — | — |
| 6SEG | Class1: CENP-A nucleosome in complex with CENP-C central region | electron microscopy | C, G | — | 10 (best 0.85) |
| 6SEG | CLASS1: cenp-a nucleosome in complex with cenp-C central region | electron microscopy | C, G | — | — |
| 6Y5D | Structure of human cGAS (K394E) bound to the nucleosome | electron microscopy | C, G, O, S | PTD | — |
| 6Y5D | Structure of human cgas (K394E) bound to the nucleosome | electron microscopy | C, G, O, S | PTD | — |
| 7JZV | Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | electron microscopy | N, n | — | 11 (best 0.84) |
| 7JZV | Cryo-EM structure of the BRCA1-UBCH5C/BARD1 E3-E2 module bound to a nucleosome | electron microscopy | N, n | — | — |
| 9FGQ | Structure of human APC3loop 375-381 bound to the NCP | electron microscopy | C, G | — | 13 (best 0.78) |
| Q6FI13 | AlphaFold monomer V2.0 prediction for histone H2A type 2-a (Q6FI13) | predicted | A | — | — |
Ligands
- PTD · Pentanedial · in 2 records
Experiment against prediction
- 6SEG chain C against the predicted model Q6FI13: TM-score 0.98, RMSD 0.54 Å
- 6SEG chain C against the predicted model Q6FI13: TM-score 0.98, RMSD 0.54 Å
- 6SEF chain C against the predicted model Q6FI13: TM-score 0.96, RMSD 0.80 Å
- 6SEF chain C against the predicted model Q6FI13: TM-score 0.96, RMSD 0.80 Å
- 7JZV chain n against the predicted model Q6FI13: TM-score 0.95, RMSD 0.94 Å
- 7JZV chain n against the predicted model Q6FI13: TM-score 0.95, RMSD 0.94 Å
- 6SEE chain C against the predicted model Q6FI13: TM-score 0.95, RMSD 0.85 Å
- 6SEE chain C against the predicted model Q6FI13: TM-score 0.95, RMSD 0.85 Å
- 6SE6 chain C against the predicted model Q6FI13: TM-score 0.95, RMSD 1.03 Å
- 6SE6 chain C against the predicted model Q6FI13: TM-score 0.95, RMSD 1.03 Å
Elsewhere
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