UniProt Q6DN90
IQ motif and SEC7 domain-containing protein 1 (Q6DN90)
IQ motif and SEC7 domain-containing protein 1 (UniProt Q6DN90): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q6DN90
- Protein
- IQ motif and SEC7 domain-containing protein 1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 8 · 2 records with a druggable one
Structures
11 records of Q6DN90 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QWM | Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing… | x-ray diffraction | A | — | — |
| 3QWM | Crystal structure of GEP100, the plextrin homology domain of iq motif and SEC7 domain-containing… | x-ray diffraction | A | — | — |
| 4C0A | Arf1(Delta1-17)in complex with BRAG2 Sec7-PH domain | x-ray diffraction | A, B, E, F | — | — |
| 4C0A | ARF1(DELTA1-17)IN complex with BRAG2 SEC7-pH domain | x-ray diffraction | A, B, E, F | — | — |
| 5NLV | Brag2 Sec7-PH (390-763) | x-ray diffraction | A | — | — |
| 5NLV | BRAG2 SEC7-pH (390-763) | x-ray diffraction | A | — | — |
| 5NLY | Brag2 Sec7-PH (390-763), P212121 | x-ray diffraction | A, B | PO4 | 5 (best 0.79) |
| 5NLY | BRAG2 SEC7-pH (390-763), P212121 | x-ray diffraction | A, B | PO4 | — |
| 6FNE | Structure of human BRAG2 (SEC7-pH domains) with the inhibitor bragsin bound to the pH domain | x-ray diffraction | A, B | DY5 | — |
| 7VMB | Crystal structure of IQSEC1-IQ motif, Sec7PH tandem in complex with calmodulin | x-ray diffraction | A, B | — | 3 (best 0.78) |
| Q6DN90 | AlphaFold monomer V2.0 prediction for iq motif and SEC7 domain- containing protein 1 (Q6DN90) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4C0A chain A against the predicted model Q6DN90: TM-score 0.99, RMSD 0.78 Å
- 4C0A chain A against the predicted model Q6DN90: TM-score 0.99, RMSD 0.78 Å
- 6FNE chain B against the predicted model Q6DN90: TM-score 0.99, RMSD 0.80 Å
- 4C0A chain F against the predicted model Q6DN90: TM-score 0.98, RMSD 0.99 Å
- 4C0A chain F against the predicted model Q6DN90: TM-score 0.98, RMSD 0.99 Å
- 6FNE chain A against the predicted model Q6DN90: TM-score 0.98, RMSD 0.91 Å
- 4C0A chain E against the predicted model Q6DN90: TM-score 0.98, RMSD 0.98 Å
- 4C0A chain E against the predicted model Q6DN90: TM-score 0.98, RMSD 0.98 Å
- 4C0A chain B against the predicted model Q6DN90: TM-score 0.98, RMSD 1.34 Å
- 4C0A chain B against the predicted model Q6DN90: TM-score 0.98, RMSD 1.34 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.