MolNFT v1 · #128289 · protein
BRAG2 SEC7-pH (390-763), P212121
5NLY · Iq motif and SEC7 domain-containing protein 1: “BRAG2 SEC7-pH (390-763), P212121”. X-ray diffraction, 1 ligand (PO4), 5 pockets (best druggability 0.79). MolNFT v1 #128289 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5NLY
- Type
- protein
- Length
- 704 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Iq motif and SEC7 domain-containing protein 1
- UniProt
- Q6DN90
- Ligands
- PO4
- Pockets
- 5 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Iq motif and SEC7 domain-containing protein 1 | protein | 353 | 46% helix, 17% strand | Q6DN90 |
| B | Iq motif and SEC7 domain-containing protein 1 | protein | 351 | 46% helix, 17% strand | Q6DN90 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 978 | 0.79 | 0.81 | 91 | empty |
| 2 | 118 | 0.56 | 0.83 | 23 | empty |
| 3 | 177 | 0.48 | 0.76 | 25 | empty |
| 4 | 156 | 0.46 | 0.76 | 21 | empty |
| 5 | 109 | 0.39 | 0.75 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 863 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 modified (artifact).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6DN90
- Elsewhere: RCSB PDB 5NLY · PDBe 5NLY · UniProt Q6DN90
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