UniProt Q6DEJ6
Sodium-dependent lysophosphatidylcholine symporter 1-B (Q6DEJ6)
Sodium-dependent lysophosphatidylcholine symporter 1-B (UniProt Q6DEJ6): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q6DEJ6
- Protein
- Sodium-dependent lysophosphatidylcholine symporter 1-B
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 28 · 7 records with a druggable one
Structures
7 records of Q6DEJ6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8D2S | Zebrafish MFSD2A isoform B in inward open ligand bound conformation | electron microscopy | A | ZGS, NA | 5 (best 0.85) |
| 8D2T | Zebrafish MFSD2A isoform B in inward open ligand-free conformation | electron microscopy | A | — | 4 (best 0.85) |
| 8D2U | Zebrafish MFSD2A isoform B in inward open ligand 1A conformation | electron microscopy | A | ZGS, NA | 4 (best 0.85) |
| 8D2V | Zebrafish MFSD2A isoform B in inward open ligand 1B conformation | electron microscopy | A | ZGS, NA | 4 (best 0.81) |
| 8D2W | Zebrafish MFSD2A isoform B in inward open ligand 2B conformation | electron microscopy | A | ZGS | 4 (best 0.84) |
| 8D2X | Zebrafish MFSD2A isoform B in inward open ligand 3C conformation | electron microscopy | A | ZGS | 3 (best 0.85) |
| Q6DEJ6 | AlphaFold monomer V2.0 prediction for sodium-dependent lysophosphatidylcholine symporter 1-B… | predicted | A | — | 4 (best 0.81) |
Ligands
Experiment against prediction
- 8D2X chain A against the predicted model Q6DEJ6: TM-score 0.79, RMSD 4.62 Å
- 8D2V chain A against the predicted model Q6DEJ6: TM-score 0.78, RMSD 4.65 Å
- 8D2W chain A against the predicted model Q6DEJ6: TM-score 0.78, RMSD 4.68 Å
- 8D2T chain A against the predicted model Q6DEJ6: TM-score 0.78, RMSD 4.64 Å
- 8D2U chain A against the predicted model Q6DEJ6: TM-score 0.78, RMSD 4.70 Å
- 8D2S chain A against the predicted model Q6DEJ6: TM-score 0.76, RMSD 4.68 Å
Elsewhere
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