MolNFT v1 · #266074 · protein
AlphaFold monomer V2.0 prediction for sodium-dependent lysophosphatidylcholine symporter 1-B (Q6DEJ6)
Q6DEJ6: “AlphaFold monomer V2.0 prediction for sodium-dependent lysophosphatidylcholine symporter 1-B (Q6DEJ6)”. 4 pockets (best druggability 0.81). MolNFT v1 #266074 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6DEJ6
- Type
- protein
- Length
- 523 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- Sodium-dependent lysophosphatidylcholine symporter 1-B
- UniProt
- Q6DEJ6
- Pockets
- 4 · best druggability 0.81
Structure
1 distinct chain · 73% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium-dependent lysophosphatidylcholine symporter 1-B | protein | 523 | 73% helix, 1% strand | Q6DEJ6 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1199 | 0.81 | 0.82 | 85 | empty |
| 2 | 72 | 0.63 | 0.91 | 19 | empty |
| 3 | 192 | 0.61 | 0.83 | 27 | empty |
| 4 | 191 | 0.45 | 0.74 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 8D2X · Zebrafish MFSD2A isoform B in inward open ligand 3C conformation · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 8D2V · Zebrafish MFSD2A isoform B in inward open ligand 1B conformation · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 8D2S · Zebrafish MFSD2A isoform B in inward open ligand bound conformation · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 8D2T · Zebrafish MFSD2A isoform B in inward open ligand-free conformation · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 8D2W · Zebrafish MFSD2A isoform B in inward open ligand 2B conformation · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 8D2U · Zebrafish MFSD2A isoform B in inward open ligand 1A conformation · an experimental structure of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6DEJ6
- Elsewhere: UniProt Q6DEJ6 · AlphaFold DB Q6DEJ6
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