UniProt Q6AXS4

Renin receptor (Q6AXS4)

Renin receptor (UniProt Q6AXS4): 19 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q6AXS4
Protein: Renin receptor
Experimental structures: 19
Predicted models: 1
Ligands: 4
Pockets: 28 · 13 records with a druggable one

Structures

20 records of Q6AXS4 in the MolNFT archive: 19 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6VQ6	Mammalian V-ATPase from rat brain - composite model of rotational state 1 bound to ADP and SidK…	electron microscopy	p	—	1 (best 0.84)
6VQ6	Mammalian V-ATPase from rat brain - composite model of rotational state 1 bound to ADP and sidk…	electron microscopy	p	—	—
6VQ7	Mammalian V-ATPase from rat brain - composite model of rotational state 2 bound to ADP and sidk…	electron microscopy	p	—	—
6VQ8	Mammalian V-ATPase from rat brain - composite model of rotational state 3 bound to ADP and SidK…	electron microscopy	p	—	1 (best 0.84)
6VQ8	Mammalian V-ATPase from rat brain - composite model of rotational state 3 bound to ADP and sidk…	electron microscopy	p	—	—
6VQC	Mammalian V-ATPase from rat brain membrane-embedded Vo region rotational state 1 (from focused…	electron microscopy	p	—	3 (best 0.84)
6VQC	Mammalian V-ATPase from rat brain membrane-embedded vo region rotational state 1 (from focused…	electron microscopy	p	—	—
6VQG	Mammalian V-ATPase from rat brain membrane-embedded Vo region rotational state 2 (from focused…	electron microscopy	p	—	3 (best 0.85)
6VQG	Mammalian V-ATPase from rat brain membrane-embedded vo region rotational state 2 (from focused…	electron microscopy	p	—	—
6VQH	Mammalian V-ATPase from rat brain membrane-embedded Vo region rotational state 3 (from focused…	electron microscopy	p	—	4 (best 0.83)
6VQH	Mammalian V-ATPase from rat brain membrane-embedded vo region rotational state 3 (from focused…	electron microscopy	p	—	—
7UZF	Rat Kidney V-ATPase with SidK, State 1	electron microscopy	p	—	1 (best 0.87)
7UZG	Rat Kidney V-ATPase lacking subunit H, with SidK and NCOA7B, State 1	electron microscopy	p	—	1 (best 0.87)
7UZH	Rat Kidney V-ATPase with SidK, State 2	electron microscopy	p	—	2 (best 0.87)
7UZI	Rat Kidney V-ATPase lacking subunit H, with SidK and NCOA7B, State 2	electron microscopy	p	—	2 (best 0.85)
9B8O	Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, Vo	electron microscopy	p	NAG, PC1, PTY, CLR	4 (best 0.84)
9BRB	Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 1	electron microscopy	p	—	1 (best 0.81)
9BRC	Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 2	electron microscopy	p	—	1 (best 0.81)
9BRD	Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3	electron microscopy	p	NAG, PC1, PTY, CLR	1 (best 0.85)
Q6AXS4	AlphaFold monomer V2.0 prediction for renin receptor (Q6AXS4)	predicted	A	—	3 (best 0.43)

Ligands

CLR · Cholesterol · in 2 records
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 2 records
PTY · Phosphatidylethanolamine · in 2 records

Experiment against prediction

9BRC chain p against the predicted model Q6AXS4: TM-score 0.64, RMSD 2.12 Å
9B8O chain p against the predicted model Q6AXS4: TM-score 0.63, RMSD 2.16 Å
9BRB chain p against the predicted model Q6AXS4: TM-score 0.63, RMSD 2.19 Å
9BRD chain p against the predicted model Q6AXS4: TM-score 0.63, RMSD 2.18 Å
7UZF chain p against the predicted model Q6AXS4: TM-score 0.62, RMSD 2.22 Å
7UZH chain p against the predicted model Q6AXS4: TM-score 0.61, RMSD 2.16 Å
7UZI chain p against the predicted model Q6AXS4: TM-score 0.61, RMSD 2.25 Å
7UZG chain p against the predicted model Q6AXS4: TM-score 0.60, RMSD 2.37 Å
6VQC chain p against the predicted model Q6AXS4: TM-score 0.59, RMSD 2.37 Å
6VQC chain p against the predicted model Q6AXS4: TM-score 0.59, RMSD 2.37 Å

Elsewhere

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