UniProt Q66DQ2
Adenine phosphoribosyltransferase (Q66DQ2)
Adenine phosphoribosyltransferase (UniProt Q66DQ2), EC 2.4.2.7: 16 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q66DQ2
- Protein
- Adenine phosphoribosyltransferase
- EC
- 2.4.2.7
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 9
- Pockets
- 14 · 7 records with a druggable one
Structures
17 records of Q66DQ2 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MB6 | Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. | x-ray diffraction | A | — | — |
| 4MB6 | Crystal structure of adenine phosphoribosyltransferase from yersinia pseudotuberculosis. | x-ray diffraction | A | — | — |
| 5B6H | Crystal structure of an APRT from Yersinia pseudotuberculosis in complex with AMP. | x-ray diffraction | A | AMP, NA, CL | 1 (best 0.57) |
| 5B6H | Crystal structure of an aprt from yersinia pseudotuberculosis in complex with AMP. | x-ray diffraction | A | — | — |
| 5Y07 | Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis with PRPP. | x-ray diffraction | A, B | PRP, NA, MG | 3 (best 0.64) |
| 5Y07 | Crystal structure of adenine phosphoribosyltransferase from yersinia pseudotuberculosis with prpp. | x-ray diffraction | A, B | PRP, NA, MG | — |
| 5Y4A | Cadmium directed assembly of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. | x-ray diffraction | A, B | NA, SO4, CD | 3 (best 0.66) |
| 5Y4A | Cadmium directed assembly of adenine phosphoribosyltransferase from yersinia pseudotuberculosis. | x-ray diffraction | A, B | NA, SO4, CD | — |
| 5ZC7 | Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (P63 space group). | x-ray diffraction | A, B | NI, ADE, NA, CL | 2 (best 0.67) |
| 5ZC7 | Crystal structure of aprt from Y. pseudotuberculosis with bound adenine (P63 space group). | x-ray diffraction | A, B | NI, ADE, NA, CL | — |
| 5ZMI | Crystal structure of APRT from Y. pseudotuberculosis in complex with adenine. | x-ray diffraction | A | ADE, NA | 1 (best 0.50) |
| 5ZMI | Crystal structure of aprt from Y. pseudotuberculosis in complex with adenine. | x-ray diffraction | A | ADE, NA | — |
| 5ZNQ | Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (P21 space group). | x-ray diffraction | A, B | ADE, NA, CL | 3 (best 0.68) |
| 5ZNQ | Crystal structure of aprt from Y. pseudotuberculosis with bound adenine (P21 space group). | x-ray diffraction | A, B | ADE, NA, CL | — |
| 5ZOC | Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (C2 space group). | x-ray diffraction | A | ADE, NA | 1 (best 0.51) |
| 5ZOC | Crystal structure of aprt from Y. pseudotuberculosis with bound adenine (C2 space group). | x-ray diffraction | A | ADE, NA | — |
| Q66DQ2 | AlphaFold monomer V2.0 prediction for adenine phosphoribosyltransferase (Q66DQ2) | predicted | A | — | — |
Ligands
- NA · Sodium ion · in 13 records
- ADE · Adenine · in 8 records
- CL · Chloride ion · in 5 records
- CD · Cadmium ion · in 2 records
- MG · Magnesium ion · in 2 records
- NI · Nickel (II) ion · in 2 records
- PRP · 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose · in 2 records
- SO4 · Sulfate ion · in 2 records
- AMP · Adenosine monophosphate · in 1 record
Experiment against prediction
- 5B6H chain A against the predicted model Q66DQ2: TM-score 1.00, RMSD 0.34 Å
- 5B6H chain A against the predicted model Q66DQ2: TM-score 1.00, RMSD 0.34 Å
- 5ZMI chain A against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.58 Å
- 5ZMI chain A against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.58 Å
- 5ZOC chain A against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.58 Å
- 5ZOC chain A against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.58 Å
- 5ZC7 chain A against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.59 Å
- 5ZC7 chain A against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.59 Å
- 5Y07 chain B against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.60 Å
- 5Y07 chain B against the predicted model Q66DQ2: TM-score 0.99, RMSD 0.60 Å
Elsewhere
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