UniProt Q63008
Sodium/iodide cotransporter (Q63008)
Sodium/iodide cotransporter (UniProt Q63008): 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q63008
- Protein
- Sodium/iodide cotransporter
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 11 · 3 records with a druggable one
Structures
3 records of Q63008 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UUZ | Structure of the sodium/iodide symporter (NIS) in complex with perrhenate and sodium | electron microscopy | A | NA, REO, 3PH | 4 (best 0.67) |
| 7UV0 | Structure of the sodium/iodide symporter (NIS) in complex with iodide and sodium | electron microscopy | A | NA, IOD, 3PH | 3 (best 0.66) |
| Q63008 | AlphaFold monomer V2.0 prediction for SODIUM/IODIDE cotransporter (Q63008) | predicted | A | — | 4 (best 0.62) |
Ligands
Experiment against prediction
- 7UUZ chain A against the predicted model Q63008: TM-score 0.96, RMSD 1.71 Å
- 7UV0 chain A against the predicted model Q63008: TM-score 0.95, RMSD 1.85 Å
Elsewhere
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