UniProt Q61234
Alpha-1-syntrophin (Q61234)
Alpha-1-syntrophin (UniProt Q61234): 12 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q61234
- Protein
- Alpha-1-syntrophin
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
13 records of Q61234 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1QAV | Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of NNOS-Syntrophin Complex | x-ray diffraction | A | — | — |
| 1QAV | Unexpected modes of PDZ domain scaffolding revealed by structure of nnos-syntrophin complex | x-ray diffraction | A | — | — |
| 1Z86 | Solution structure of the PDZ domain of alpha-syntrophin | solution nmr | A | — | — |
| 1Z86 | Solution structure of the PDZ domain of alpha-syntrophin | solution nmr | A | — | — |
| 1Z87 | solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin | solution nmr | A | — | — |
| 1Z87 | Solution structure of the split pH-PDZ supramodule of alpha-syntrophin | solution nmr | A | — | — |
| 2ADZ | solution structure of the joined PH domain of alpha1-syntrophin | solution nmr | A | — | — |
| 2ADZ | Solution structure of the joined pH domain of ALPHA1-syntrophin | solution nmr | A | — | — |
| 2PDZ | Solution structure of the syntrophin PDZ domain in complex with the peptide gvkeslv, NMR, 15… | solution nmr | A | — | — |
| 2PDZ | Solution structure of the syntrophin PDZ domain in complex with the peptide gvkeslv, NMR, 15… | solution nmr | A | — | — |
| 4HOP | Crystal structure of the computationally designed NNOS-Syntrophin complex | x-ray diffraction | A, C, E | — | — |
| 4HOP | Crystal structure of the computationally designed nnos-syntrophin complex | x-ray diffraction | A, C, E | — | — |
| Q61234 | AlphaFold monomer V2.0 prediction for alpha-1-syntrophin (Q61234) | predicted | A | — | 4 (best 0.57) |
Experiment against prediction
- 1QAV chain A against the predicted model Q61234: TM-score 0.95, RMSD 0.87 Å
- 1QAV chain A against the predicted model Q61234: TM-score 0.95, RMSD 0.87 Å
- 4HOP chain E against the predicted model Q61234: TM-score 0.94, RMSD 1.03 Å
- 4HOP chain E against the predicted model Q61234: TM-score 0.94, RMSD 1.03 Å
- 4HOP chain A against the predicted model Q61234: TM-score 0.93, RMSD 1.03 Å
- 4HOP chain A against the predicted model Q61234: TM-score 0.93, RMSD 1.03 Å
- 1Z86 chain A against the predicted model Q61234: TM-score 0.89, RMSD 1.33 Å
- 1Z86 chain A against the predicted model Q61234: TM-score 0.89, RMSD 1.33 Å
- 2PDZ chain A against the predicted model Q61234: TM-score 0.88, RMSD 1.44 Å
- 2PDZ chain A against the predicted model Q61234: TM-score 0.88, RMSD 1.44 Å
Elsewhere
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