UniProt Q60793
Krueppel-like factor 4 (Q60793)
Krueppel-like factor 4 (UniProt Q60793): 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q60793
- Protein
- Krueppel-like factor 4
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 2 records with a druggable one
Structures
17 records of Q60793 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WBS | Crystal structure of the zinc finger domain of Klf4 bound to its target DNA | x-ray diffraction | A | — | — |
| 2WBS | Crystal structure of the zinc finger domain of KLF4 bound to its target DNA | x-ray diffraction | A | — | — |
| 2WBU | Crystal structure of the zinc finger domain of KLF4 bound to its target DNA | x-ray diffraction | A | — | — |
| 2WBU | Crystal structure of the zinc finger domain of KLF4 bound to its target DNA | x-ray diffraction | A | — | — |
| 4M9E | Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA | x-ray diffraction | A | — | — |
| 4M9E | Structure of KLF4 zinc finger DNA binding domain in complex with methylated DNA | x-ray diffraction | A | — | — |
| 5KE6 | Mouse KLF4 ZNF1-3 and TPG/CPA sequence DNA complex structure | x-ray diffraction | A | ZN | — |
| 5KE7 | mouse Klf4 ZnF1-3 and TpG/MpA sequence DNA complex structure | x-ray diffraction | A | ZN | — |
| 5KE7 | Mouse KLF4 ZNF1-3 and TPG/MPA sequence DNA complex structure | x-ray diffraction | A | ZN | — |
| 5KE8 | mouse Klf4 E446P ZnF1-3 and MpG/MpG sequence DNA complex structure | x-ray diffraction | A | ZN | — |
| 5KE8 | Mouse KLF4 E446P ZNF1-3 and MPG/MPG sequence DNA complex structure | x-ray diffraction | A | ZN | — |
| 5KE9 | mouse Klf4 E446P ZnF1-3 and TpG/CpA sequence DNA complex structure | x-ray diffraction | A | ZN | 2 (best 0.64) |
| 5KE9 | Mouse KLF4 E446P ZNF1-3 and TPG/CPA sequence DNA complex structure | x-ray diffraction | A | ZN | — |
| 5KEA | Mouse KLF4 ZNF1-3 (E446D) and CPG/CPG sequence DNA complex structure: form I | x-ray diffraction | A | ZN | — |
| 5KEB | mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form II | x-ray diffraction | A | ZN | 1 (best 0.75) |
| 5KEB | Mouse KLF4 ZNF1-3 (E446D) and CPG/CPG sequence DNA complex structure: form II | x-ray diffraction | A | ZN | — |
| Q60793 | AlphaFold monomer V2.0 prediction for krueppel-like factor 4 (Q60793) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 10 records
Experiment against prediction
- 5KE8 chain A against the predicted model Q60793: TM-score 0.94, RMSD 0.86 Å
- 5KE8 chain A against the predicted model Q60793: TM-score 0.94, RMSD 0.86 Å
- 5KEA chain A against the predicted model Q60793: TM-score 0.91, RMSD 0.91 Å
- 5KE7 chain A against the predicted model Q60793: TM-score 0.91, RMSD 1.16 Å
- 5KE7 chain A against the predicted model Q60793: TM-score 0.91, RMSD 1.16 Å
- 5KE6 chain A against the predicted model Q60793: TM-score 0.91, RMSD 1.15 Å
- 4M9E chain A against the predicted model Q60793: TM-score 0.91, RMSD 1.15 Å
- 4M9E chain A against the predicted model Q60793: TM-score 0.91, RMSD 1.15 Å
- 2WBU chain A against the predicted model Q60793: TM-score 0.90, RMSD 1.19 Å
- 2WBU chain A against the predicted model Q60793: TM-score 0.90, RMSD 1.19 Å
Elsewhere
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