UniProt Q5ZKX9
ER lumen protein-retaining receptor 2 (Q5ZKX9)
ER lumen protein-retaining receptor 2 (UniProt Q5ZKX9): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5ZKX9
- Protein
- ER lumen protein-retaining receptor 2
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 4 records with a druggable one
Structures
18 records of Q5ZKX9 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6I6B | Crystal structure of the KDEL receptor in the peptide free state. | x-ray diffraction | A | — | 1 (best 0.71) |
| 6I6B | Crystal structure of the kdel receptor in the peptide free state. | x-ray diffraction | A | — | — |
| 6I6H | Crystal structure of the KDEL receptor in the peptide bound state | x-ray diffraction | A | — | 1 (best 0.51) |
| 6I6H | Crystal structure of the kdel receptor in the peptide bound state | x-ray diffraction | A | — | — |
| 6I6J | Crystal structure of the KDEL receptor bound to synthetic nanobody. | x-ray diffraction | A | — | — |
| 6I6J | Crystal structure of the kdel receptor bound to synthetic nanobody. | x-ray diffraction | A | — | — |
| 6Y7V | Crystal structure of the KDEL receptor bound to HDEL peptide at pH 6.0 | x-ray diffraction | A | CO2 | — |
| 6Y7V | Crystal structure of the kdel receptor bound to hdel peptide at pH 6.0 | x-ray diffraction | A | CO2 | — |
| 6ZXR | Crystal structure of the KDEL receptor bound to RDEL peptide at pH 6.0 | x-ray diffraction | A | — | 1 (best 0.43) |
| 6ZXR | Crystal structure of the kdel receptor bound to rdel peptide at pH 6.0 | x-ray diffraction | A | — | — |
| 7OXE | Crystal structure of the KDEL receptor bound to HDEF peptide at pH 6.0 | x-ray diffraction | A | — | — |
| 7OXE | Crystal structure of the kdel receptor bound to hdef peptide at pH 6.0 | x-ray diffraction | A | — | — |
| 7OYE | Crystal structure of the KDEL receptor bound to HDEL peptide at pH 7.0 | x-ray diffraction | A | CO2 | 1 (best 0.32) |
| 7OYE | Crystal structure of the kdel receptor bound to hdel peptide at pH 7.0 | x-ray diffraction | A | CO2 | — |
| 7RXC | CryoEM structure of KDELR with Legobody | electron microscopy | K | POV | 3 (best 0.78) |
| 7RXC | Cryoem structure of kdelr with legobody | electron microscopy | K | POV | — |
| 8APY | Crystal structure of the H12A variant of the KDEL receptor bound to sybody | x-ray diffraction | A | — | 3 (best 0.79) |
| Q5ZKX9 | AlphaFold monomer V2.0 prediction for er lumen protein-retaining receptor 2 (Q5ZKX9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7OYE chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.57 Å
- 7OYE chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.57 Å
- 6I6H chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.60 Å
- 6I6H chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.60 Å
- 7OXE chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.62 Å
- 7OXE chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.62 Å
- 6Y7V chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.64 Å
- 6Y7V chain A against the predicted model Q5ZKX9: TM-score 0.99, RMSD 0.64 Å
- 6ZXR chain A against the predicted model Q5ZKX9: TM-score 0.98, RMSD 0.82 Å
- 6ZXR chain A against the predicted model Q5ZKX9: TM-score 0.98, RMSD 0.82 Å
Elsewhere
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