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MolNFT v1 · #186996 · protein

Cryoem structure of kdelr with legobody

7RXC: “Cryoem structure of kdelr with legobody”. Electron microscopy, 2 ligands (POV, GLC). MolNFT v1 #186996 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7RXC
Type
protein
Length
1,178 residues
Chains
5
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A4Z0THX4, P99134, P06654, Q5ZKX9
Ligands
POV, GLC

Structure

electron microscopy · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
H—protein207——
L—protein204——
N—protein126——
B—protein439—A0A4Z0THX4, P99134, P06654
K—protein202—Q5ZKX9

Ligands and binding sites

  • POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · ligand · 4 copies · chains K
  • GLC · alpha-D-glucopyranose · sugar · 2 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7RXC · CryoEM structure of KDELR with Legobody · the same entry in another collection · chain K against K, TM-score 1.00
  • Q5ZKX9 · AlphaFold monomer V2.0 prediction for er lumen protein-retaining receptor 2 (Q5ZKX9) · a predicted model of the same protein · chain K against A, TM-score 0.93
  • P06654 · AlphaFold monomer V2.0 prediction for immunoglobulin G-binding protein G (P06654) · a predicted model of the same protein · chain B against A, TM-score 0.18
  • P99134 · AlphaFold monomer V2.0 prediction for immunoglobulin G-binding protein a (P99134) · a predicted model of the same protein · chain B against A, TM-score 0.18

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