UniProt Q5SRI9
Glycoprotein endo-alpha-1,2-mannosidase (Q5SRI9)
Glycoprotein endo-alpha-1,2-mannosidase (UniProt Q5SRI9), EC 3.2.1.130: 7 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q5SRI9
- Protein
- Glycoprotein endo-alpha-1,2-mannosidase
- EC
- 3.2.1.130
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 28 · 5 records with a druggable one
Structures
8 records of Q5SRI9 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZDC | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with nickel | x-ray diffraction | A | NI | 4 (best 0.54) |
| 6ZDC | Structure of the catalytic domain of human endo-alpha-mannosidase manea in complex with nickel | x-ray diffraction | A | NI | — |
| 6ZDF | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with HEPES | x-ray diffraction | A, B, C | — | 14 (best 0.86) |
| 6ZDF | Structure of the catalytic domain of human endo-alpha-mannosidase manea in complex with hepes | x-ray diffraction | A, B, C | — | — |
| 6ZDL | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG and… | x-ray diffraction | AAA | MG, TEW, IFM, GLC | 4 (best 0.60) |
| 6ZFQ | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with bis-tris | x-ray diffraction | AAA | — | 3 (best 0.63) |
| 6ZJ5 | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcDMJ and… | x-ray diffraction | AAA | TEW, DMJ, GLC | 3 (best 0.58) |
| Q5SRI9 | AlphaFold monomer V2.0 prediction for glycoprotein endo- alpha-1,2-mannosidase (Q5SRI9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6ZDF chain B against the predicted model Q5SRI9: TM-score 1.00, RMSD 0.43 Å
- 6ZDF chain B against the predicted model Q5SRI9: TM-score 1.00, RMSD 0.43 Å
- 6ZDF chain C against the predicted model Q5SRI9: TM-score 1.00, RMSD 0.50 Å
- 6ZDF chain C against the predicted model Q5SRI9: TM-score 1.00, RMSD 0.50 Å
- 6ZDF chain A against the predicted model Q5SRI9: TM-score 0.99, RMSD 0.62 Å
- 6ZDF chain A against the predicted model Q5SRI9: TM-score 0.99, RMSD 0.62 Å
- 6ZDL chain AAA against the predicted model Q5SRI9: TM-score 0.99, RMSD 0.72 Å
- 6ZFQ chain AAA against the predicted model Q5SRI9: TM-score 0.99, RMSD 0.92 Å
- 6ZJ5 chain AAA against the predicted model Q5SRI9: TM-score 0.99, RMSD 0.83 Å
- 6ZDC chain A against the predicted model Q5SRI9: TM-score 0.98, RMSD 1.36 Å
Elsewhere
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