UniProt Q5SHR6
DNA-directed RNA polymerase subunit alpha (Q5SHR6)
DNA-directed RNA polymerase subunit alpha (UniProt Q5SHR6), EC 2.7.7.6: 84 experimental structures on GenesisL1, 1 ligand bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q5SHR6
- Protein
- DNA-directed RNA polymerase subunit alpha
- EC
- 2.7.7.6
- Experimental structures
- 84
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 34 · 7 records with a druggable one
Structures
84 records of Q5SHR6 in the MolNFT archive: 84 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZYR | Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic… | x-ray diffraction | A, B, K, L | — | — |
| 1ZYR | Structure of thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic… | x-ray diffraction | A, B, K, L | — | — |
| 2A6E | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme | x-ray diffraction | A, B, K, L | — | — |
| 2A6E | Crystal structure of the T. thermophilus RNA polymerase holoenzyme | x-ray diffraction | A, B, K, L | — | — |
| 2A6H | Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic… | x-ray diffraction | A, B, K, L | — | — |
| 2A6H | Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic… | x-ray diffraction | A, B, K, L | — | — |
| 2CW0 | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution | x-ray diffraction | A, B, K, L | — | — |
| 2CW0 | Crystal structure of thermus thermophilus RNA polymerase holoenzyme at 3.3 ångströms resolution | x-ray diffraction | A, B, K, L | — | — |
| 2O5I | Crystal structure of the T. thermophilus RNA polymerase elongation complex | x-ray diffraction | A, B, K, L | — | — |
| 2O5I | Crystal structure of the T. thermophilus RNA polymerase elongation complex | x-ray diffraction | A, B, K, L | — | — |
| 2O5J | Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the NTP substrate… | x-ray diffraction | A, B, K, L | — | — |
| 2O5J | Crystal structure of the T. thermophilus rnap polymerase elongation complex with the ntp substrate… | x-ray diffraction | A, B, K, L | — | — |
| 3AOH | RNA polymerase-Gfh1 complex (Crystal type 1) | x-ray diffraction | A, B, F, G, K, L | — | — |
| 3AOH | RNA polymerase-GFH1 complex (crystal type 1) | x-ray diffraction | A, B, F, G, K, L | — | — |
| 3AOI | RNA polymerase-Gfh1 complex (Crystal type 2) | x-ray diffraction | A, B, F, G, K, L | — | — |
| 3AOI | RNA polymerase-GFH1 complex (crystal type 2) | x-ray diffraction | A, B, F, G, K, L | — | — |
| 3DXJ | Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic… | x-ray diffraction | A, B, K, L | — | — |
| 3DXJ | Crystal structure of thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic… | x-ray diffraction | A, B, K, L | — | — |
| 3WOD | RNA polymerase-gp39 complex | x-ray diffraction | A, B | — | — |
| 3WOD | RNA polymerase-GP39 complex | x-ray diffraction | A, B | — | — |
| 4G7H | Crystal structure of Thermus thermophilus transcription initiation complex | x-ray diffraction | A, B, K, L | — | — |
| 4G7H | Crystal structure of thermus thermophilus transcription initiation complex | x-ray diffraction | A, B, K, L | — | — |
| 4G7O | Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA | x-ray diffraction | A, B, K, L | — | — |
| 4G7O | Crystal structure of thermus thermophilus transcription initiation complex containing 2 nt of RNA | x-ray diffraction | A, B, K, L | — | — |
| 4G7Z | Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at… | x-ray diffraction | A, B, K, L | — | — |
| 4G7Z | Crystal structure of thermus thermophilus transcription initiation complex containing 5-bru at… | x-ray diffraction | A, B, K, L | — | — |
| 4GZY | Crystal structures of bacterial RNA Polymerase paused elongation complexes | x-ray diffraction | A, B | — | — |
| 4GZY | Crystal structures of bacterial RNA polymerase paused elongation complexes | x-ray diffraction | A, B | — | — |
| 4GZZ | Crystal structures of bacterial RNA Polymerase paused elongation complexes | x-ray diffraction | A, B | — | — |
| 4GZZ | Crystal structures of bacterial RNA polymerase paused elongation complexes | x-ray diffraction | A, B | — | — |
| 4MQ9 | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 | x-ray diffraction | A, B | — | — |
| 4MQ9 | Crystal structure of thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 | x-ray diffraction | A, B | — | — |
| 4OIN | Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 | x-ray diffraction | A, B | — | — |
| 4OIN | Crystal structure of thermus thermophilus transcription initiation complex soaked with GE23077 | x-ray diffraction | A, B | — | — |
| 4OIO | Crystal structure of Thermus thermophilus pre-insertion substrate complex for de novo transcription… | x-ray diffraction | A, B | — | — |
| 4OIO | Crystal structure of thermus thermophilus pre-insertion substrate complex for de novo transcription… | x-ray diffraction | A, B | — | — |
| 4OIP | Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077… | x-ray diffraction | A, B | — | — |
| 4OIP | Crystal structure of thermus thermophilus transcription initiation complex soaked with GE23077… | x-ray diffraction | A, B | — | — |
| 4OIQ | Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 and… | x-ray diffraction | A, B | — | — |
| 4OIQ | Crystal structure of thermus thermophilus transcription initiation complex soaked with GE23077 and… | x-ray diffraction | A, B | — | — |
| 4OIR | Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked… | x-ray diffraction | A, B | — | — |
| 4OIR | Crystal structure of thermus thermophilus RNA polymerase transcription initiation complex soaked… | x-ray diffraction | A, B | — | — |
| 4WQS | Thermus thermophilus RNA polymerase backtracked complex | x-ray diffraction | A, B, K, L | — | — |
| 4WQT | Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GREA/GFH1… | x-ray diffraction | A, B, F, G, K, L | — | — |
| 5I2D | Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo | x-ray diffraction | A, B, L, M | — | 3 (best 0.85) |
| 5I2D | Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: tap-rpo | x-ray diffraction | A, B, L, M | — | — |
| 5VO8 | X-ray crystal structure of a bacterial reiterative transcription complex of pyrg promoter | x-ray diffraction | A, B | MG | — |
| 5XJ0 | T. thermophilus RNA polymerase holoenzyme bound with GP39 and GP76 | x-ray diffraction | A, B | — | — |
| 6ASG | Crystal structure of Thermus thermophilus RNA polymerase core enzyme | x-ray diffraction | A, B | — | 7 (best 0.87) |
| 6ASG | Crystal structure of thermus thermophilus RNA polymerase core enzyme | x-ray diffraction | A, B | — | — |
| 6KQD | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 3 nt | x-ray diffraction | A, B, K, L | MG | — |
| 6KQD | Thermus thermophilus initial transcription complex comprising sigma a and 5'-oh RNA of 3 nt | x-ray diffraction | A, B, K, L | MG | — |
| 6KQE | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 4 nt | x-ray diffraction | A, B | MG | — |
| 6KQE | Thermus thermophilus initial transcription complex comprising sigma a and 5'-oh RNA of 4 nt | x-ray diffraction | A, B | MG | — |
| 6KQF | Thermus thermophilus initial transcription complex comprising sigma a and 5'-oh RNA of 5 nt | x-ray diffraction | A, B | MG | — |
| 6KQG | Thermus thermophilus initial transcription complex comprising sigma a and 5'-oh RNA of 6 nt | x-ray diffraction | A, B | MG | — |
| 6KQH | Thermus thermophilus initial transcription complex comprising sigma a and 5'-oh RNA of 7 nt | x-ray diffraction | A, B | MG | — |
| 6KQL | Thermus thermophilus initial transcription complex comprising sigma a and 5'-triphosphate RNA of 4… | x-ray diffraction | A, B | MG | — |
| 6KQM | Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 5… | x-ray diffraction | A, B | MG | — |
| 6KQM | Thermus thermophilus initial transcription complex comprising sigma a and 5'-triphosphate RNA of 5… | x-ray diffraction | A, B | MG | — |
24 records more on the page itself.
Ligands
- MG · Magnesium ion · in 28 records
Elsewhere
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