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UniProt Q5SGE1

Heparosan synthase B (Q5SGE1)

Heparosan synthase B (UniProt Q5SGE1): 3 experimental structures on GenesisL1, 7 ligands bound, 53 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q5SGE1
Protein
Heparosan synthase B
Experimental structures
3
Predicted models
0
Ligands
7
Pockets
53 · 3 records with a druggable one

Structures

3 records of Q5SGE1 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8VH7Crystal structure of heparosan synthase 2 from Pasteurella multocida at 1.98 Ax-ray diffractionA, BMN, UDP, NA13 (best 0.78)
8VH8Crystal structure of heparosan synthase 2 from Pasteurella multocida at 2.85 Ax-ray diffractionA, B, C, DMN, UDP, NA, CL, CA20 (best 0.77)
8VIWCryo-EM structure of heparosan synthase 2 from Pasteurella multocida with polysaccharide in the…electron microscopyA, B, C, DGNS, BDP, MN, UDP20 (best 0.79)

Ligands

  • MN · Manganese (II) ion · in 3 records
  • UDP · Uridine-5'-diphosphate · in 3 records
  • NA · Sodium ion · in 2 records
  • BDP · beta-D-glucopyranuronic acid · in 1 record
  • CA · Calcium ion · in 1 record
  • CL · Chloride ion · in 1 record
  • GNS · 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose · in 1 record

Elsewhere

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