UniProt Q5MNZ6
WD repeat domain phosphoinositide-interacting protein 3 (Q5MNZ6)
WD repeat domain phosphoinositide-interacting protein 3 (UniProt Q5MNZ6): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 32 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q5MNZ6
- Protein
- WD repeat domain phosphoinositide-interacting protein 3
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 32 · 5 records with a druggable one
Structures
8 records of Q5MNZ6 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6IYY | Crystal structure of human WIPI3,loop deletion mutant | x-ray diffraction | A | SO4 | — |
| 6IYY | Crystal structure of human WIPI3,LOOP deletion mutant | x-ray diffraction | A | SO4 | — |
| 6KLR | Crystal structure of human WIPI3 in complex with the WIR-peptide from ATG2A | x-ray diffraction | A, B | — | 4 (best 0.77) |
| 6KLR | Crystal structure of human WIPI3 in complex with the wir-peptide from ATG2A | x-ray diffraction | A, B | — | — |
| 8ZQG | Crystal structure of WIPI3 in complex with ATG16L1 | x-ray diffraction | B, A | — | 7 (best 0.77) |
| 9C9I | Structure of the TSC1:WIPI3 complex | x-ray diffraction | A, C, E, G | — | 14 (best 0.79) |
| 9CE3 | Structure of the TSC:WIPI3 lysosomal recruitment complex | electron microscopy | F | — | 3 (best 0.77) |
| Q5MNZ6 | AlphaFold monomer V2.0 prediction for wd repeat domain phosphoinositide-interacting protein 3… | predicted | A | — | 4 (best 0.81) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 8ZQG chain A against the predicted model Q5MNZ6: TM-score 0.99, RMSD 0.70 Å
- 8ZQG chain B against the predicted model Q5MNZ6: TM-score 0.99, RMSD 0.73 Å
- 9C9I chain A against the predicted model Q5MNZ6: TM-score 0.98, RMSD 0.95 Å
- 9C9I chain E against the predicted model Q5MNZ6: TM-score 0.98, RMSD 0.95 Å
- 6KLR chain A against the predicted model Q5MNZ6: TM-score 0.98, RMSD 0.99 Å
- 6KLR chain A against the predicted model Q5MNZ6: TM-score 0.98, RMSD 0.99 Å
- 9CE3 chain F against the predicted model Q5MNZ6: TM-score 0.98, RMSD 0.98 Å
- 9C9I chain C against the predicted model Q5MNZ6: TM-score 0.98, RMSD 1.09 Å
- 9C9I chain G against the predicted model Q5MNZ6: TM-score 0.98, RMSD 1.09 Å
- 6IYY chain A against the predicted model Q5MNZ6: TM-score 0.97, RMSD 1.39 Å
Elsewhere
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