UniProt Q5E9K0
Proteasome subunit beta type-2 (Q5E9K0)
Proteasome subunit beta type-2 (UniProt Q5E9K0), EC 3.4.25.1: 9 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5E9K0
- Protein
- Proteasome subunit beta type-2
- EC
- 3.4.25.1
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 15 · 6 records with a druggable one
Structures
10 records of Q5E9K0 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28alpha-beta in complex with immunoproteasome | electron microscopy | I, T | — | 2 (best 0.78) |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | I, T | — | — |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | I, T | — | 3 (best 0.76) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | I, T | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | l, T | — | 2 (best 0.84) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | l, T | — | — |
| 8AZK | Bovine 20S proteasome, untreated | electron microscopy | K, Y | — | 2 (best 0.75) |
| 8FZ5 | The PI31-free Bovine 20S proteasome | electron microscopy | K, Y | — | 3 (best 0.79) |
| 8FZ6 | The human PI31 complexed with bovine 20S proteasome | electron microscopy | K, Y | — | 3 (best 0.80) |
| Q5E9K0 | AlphaFold monomer V2.0 prediction for proteasome subunit beta type-2 (Q5E9K0) | predicted | A | — | — |
Experiment against prediction
- 8FZ6 chain K against the predicted model Q5E9K0: TM-score 1.00, RMSD 0.27 Å
- 8FZ5 chain K against the predicted model Q5E9K0: TM-score 1.00, RMSD 0.30 Å
- 7DR7 chain T against the predicted model Q5E9K0: TM-score 0.99, RMSD 0.52 Å
- 7DR7 chain T against the predicted model Q5E9K0: TM-score 0.99, RMSD 0.52 Å
- 7DR7 chain I against the predicted model Q5E9K0: TM-score 0.99, RMSD 0.52 Å
- 7DR7 chain I against the predicted model Q5E9K0: TM-score 0.99, RMSD 0.52 Å
- 8AZK chain Y against the predicted model Q5E9K0: TM-score 0.99, RMSD 0.63 Å
- 8AZK chain K against the predicted model Q5E9K0: TM-score 0.99, RMSD 0.64 Å
- 7DR6 chain T against the predicted model Q5E9K0: TM-score 0.98, RMSD 0.70 Å
- 7DR6 chain T against the predicted model Q5E9K0: TM-score 0.98, RMSD 0.70 Å
Elsewhere
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