UniProt Q5E987
Proteasome subunit alpha type-5 (Q5E987)
Proteasome subunit alpha type-5 (UniProt Q5E987): 9 experimental structures and 1 predicted model on GenesisL1, 52 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5E987
- Protein
- Proteasome subunit alpha type-5
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 52 · 9 records with a druggable one
Structures
10 records of Q5E987 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28alpha-beta in complex with immunoproteasome | electron microscopy | P, b | — | 3 (best 0.84) |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | P, b | — | 3 (best 0.84) |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | B, P | — | 6 (best 0.76) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | B, P | — | 6 (best 0.76) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | E, R | — | 7 (best 0.81) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | E, R | — | 7 (best 0.81) |
| 8AZK | Bovine 20S proteasome, untreated | electron microscopy | E, S | — | 6 (best 0.77) |
| 8FZ5 | The PI31-free Bovine 20S proteasome | electron microscopy | E, S | — | 6 (best 0.74) |
| 8FZ6 | The human PI31 complexed with bovine 20S proteasome | electron microscopy | E, S | — | 6 (best 0.78) |
| Q5E987 | AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-5 (Q5E987) | predicted | A | — | 2 (best 0.31) |
Experiment against prediction
- 7DR7 chain B against the predicted model Q5E987: TM-score 0.96, RMSD 1.31 Å
- 7DR7 chain B against the predicted model Q5E987: TM-score 0.96, RMSD 1.31 Å
- 8FZ6 chain E against the predicted model Q5E987: TM-score 0.96, RMSD 1.54 Å
- 8FZ5 chain E against the predicted model Q5E987: TM-score 0.96, RMSD 1.67 Å
- 7DRW chain E against the predicted model Q5E987: TM-score 0.95, RMSD 1.43 Å
- 7DRW chain E against the predicted model Q5E987: TM-score 0.95, RMSD 1.43 Å
- 8AZK chain S against the predicted model Q5E987: TM-score 0.95, RMSD 1.46 Å
- 7DR6 chain P against the predicted model Q5E987: TM-score 0.95, RMSD 1.49 Å
- 7DR6 chain P against the predicted model Q5E987: TM-score 0.95, RMSD 1.49 Å
- 8AZK chain E against the predicted model Q5E987: TM-score 0.94, RMSD 1.66 Å
Elsewhere
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