UniProt Q58DU5
Proteasome subunit alpha type-3 (Q58DU5)
Proteasome subunit alpha type-3 (UniProt Q58DU5): 7 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q58DU5
- Protein
- Proteasome subunit alpha type-3
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 18 · 4 records with a druggable one
Structures
8 records of Q58DU5 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | R, d | — | — |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | D, R | — | 4 (best 0.76) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | D, R | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | G, d | — | — |
| 8AZK | Bovine 20S proteasome, untreated | electron microscopy | G, U | — | 5 (best 0.76) |
| 8FZ5 | The PI31-free Bovine 20S proteasome | electron microscopy | G, U | — | 5 (best 0.74) |
| 8FZ6 | The human PI31 complexed with bovine 20S proteasome | electron microscopy | G, U | — | 2 (best 0.74) |
| Q58DU5 | AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-3 (Q58DU5) | predicted | A | — | 2 (best 0.42) |
Experiment against prediction
- 8FZ5 chain U against the predicted model Q58DU5: TM-score 1.00, RMSD 0.30 Å
- 8FZ6 chain G against the predicted model Q58DU5: TM-score 1.00, RMSD 0.30 Å
- 8FZ5 chain G against the predicted model Q58DU5: TM-score 1.00, RMSD 0.30 Å
- 8FZ6 chain U against the predicted model Q58DU5: TM-score 1.00, RMSD 0.31 Å
- 7DR7 chain R against the predicted model Q58DU5: TM-score 0.98, RMSD 0.75 Å
- 7DR7 chain D against the predicted model Q58DU5: TM-score 0.98, RMSD 0.75 Å
- 7DR7 chain D against the predicted model Q58DU5: TM-score 0.98, RMSD 0.75 Å
- 8AZK chain G against the predicted model Q58DU5: TM-score 0.98, RMSD 0.83 Å
- 7DR6 chain R against the predicted model Q58DU5: TM-score 0.98, RMSD 0.92 Å
- 8AZK chain U against the predicted model Q58DU5: TM-score 0.97, RMSD 1.02 Å
Elsewhere
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