UniProt Q54089
Bifunctional RELA/SPOT (Q54089)
Bifunctional RELA/SPOT (UniProt Q54089), EC 2.7.6.5, 3.1.7.2: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q54089
- Protein
- Bifunctional RELA/SPOT
- EC
- 2.7.6.5, 3.1.7.2
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 13 · 2 records with a druggable one
Structures
3 records of Q54089 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1VJ7 | Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from… | x-ray diffraction | A, B | MN, GDP, GPX | 10 (best 0.64) |
| 1VJ7 | Crystal structure of the bifunctional catalytic fragment of relseq, the RELA/SPOT homolog from… | x-ray diffraction | A, B | — | — |
| Q54089 | AlphaFold monomer V2.0 prediction for bifunctional (P)PPGPP SYNTHASE/HYDROLASE rela (Q54089) | predicted | A | — | 3 (best 0.76) |
Ligands
Experiment against prediction
- 1VJ7 chain A against the predicted model Q54089: TM-score 0.96, RMSD 1.65 Å
- 1VJ7 chain A against the predicted model Q54089: TM-score 0.96, RMSD 1.65 Å
- 1VJ7 chain B against the predicted model Q54089: TM-score 0.95, RMSD 1.76 Å
- 1VJ7 chain B against the predicted model Q54089: TM-score 0.95, RMSD 1.76 Å
Elsewhere
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