GL1X · GenesisL1 explorer

UniProt Q53Z63

5'-nucleotidase, ecto (CD73), isoform CRA_a (Q53Z63)

5'-nucleotidase, ecto (CD73), isoform CRA_a (UniProt Q53Z63), EC 3.1.3.5: 6 experimental structures on GenesisL1, 6 ligands bound, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q53Z63
Protein
5'-nucleotidase, ecto (CD73), isoform CRA_a
EC
3.1.3.5
Experimental structures
6
Predicted models
0
Ligands
6
Pockets
27 · 3 records with a druggable one

Structures

6 records of Q53Z63 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6TVGHuman CD73 (ecto 5'-nucleotidase) in complex with AMPCP in the open statex-ray diffractionAZN, AP2, NA, CA5 (best 0.66)
6TVGHuman CD73 (ecto 5'-nucleotidase) in complex with ampcp in the open statex-ray diffractionAZN, AP2, NA, CA—
6VC9TB19 complexx-ray diffractionANAG, ZN, PO45 (best 0.78)
6VC9TB19 complexx-ray diffractionANAG, ZN, PO4—
6VCATB38 complexx-ray diffractionA, B, C, DNAG17 (best 0.86)
6VCATB38 complexx-ray diffractionA, B, C, DNAG—

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • ZN · Zinc ion · in 4 records
  • AP2 · Phosphomethylphosphonic acid adenosyl ester · in 2 records
  • CA · Calcium ion · in 2 records
  • NA · Sodium ion · in 2 records
  • PO4 · Phosphate ion · in 2 records

Elsewhere

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