UniProt Q53EZ4
Centrosomal protein of 55 kDa (Q53EZ4)
Centrosomal protein of 55 kDa (UniProt Q53EZ4): 8 experimental structures and 1 predicted model on GenesisL1, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q53EZ4
- Protein
- Centrosomal protein of 55 kDa
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 20 · 4 records with a druggable one
Structures
9 records of Q53EZ4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3E1R | Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55 | x-ray diffraction | A, B | — | — |
| 3E1R | Midbody targeting of the escrt machinery by a non-canonical coiled-coil in CEP55 | x-ray diffraction | A, B | — | — |
| 3WUT | Structure basis of inactivating cell abscission | x-ray diffraction | A, B, D, E, G, H, J, K | — | 3 (best 0.47) |
| 3WUT | Structure basis of inactivating cell abscission | x-ray diffraction | A, B, D, E, G, H, J, K | — | 3 (best 0.47) |
| 3WUU | Structure basis of inactivating cell abscission with chimera peptide 1 | x-ray diffraction | A, B, D, E, G, H, J, K | — | 3 (best 0.57) |
| 3WUU | Structure basis of inactivating cell abscission with chimera peptide 1 | x-ray diffraction | A, B, D, E, G, H, J, K | — | 3 (best 0.57) |
| 3WUV | Structure basis of inactivating cell abscission with chimera peptide 2 | x-ray diffraction | A, B, D, E, G, H, J, K, M, N, P, Q | — | 4 (best 0.75) |
| 3WUV | Structure basis of inactivating cell abscission with chimera peptide 2 | x-ray diffraction | A, B, D, E, G, H, J, K, M, N, P, Q | — | 4 (best 0.75) |
| Q53EZ4 | AlphaFold monomer V2.0 prediction for centrosomal protein of 55 kda (Q53EZ4) | predicted | A | — | — |
Experiment against prediction
- 3WUU chain K against the predicted model Q53EZ4: TM-score 0.91, RMSD 0.89 Å
- 3WUU chain K against the predicted model Q53EZ4: TM-score 0.91, RMSD 0.89 Å
- 3WUU chain B against the predicted model Q53EZ4: TM-score 0.91, RMSD 0.82 Å
- 3WUU chain B against the predicted model Q53EZ4: TM-score 0.91, RMSD 0.82 Å
- 3E1R chain A against the predicted model Q53EZ4: TM-score 0.91, RMSD 0.72 Å
- 3E1R chain A against the predicted model Q53EZ4: TM-score 0.91, RMSD 0.72 Å
- 3WUU chain E against the predicted model Q53EZ4: TM-score 0.90, RMSD 0.80 Å
- 3WUU chain E against the predicted model Q53EZ4: TM-score 0.90, RMSD 0.80 Å
- 3WUT chain H against the predicted model Q53EZ4: TM-score 0.90, RMSD 0.80 Å
- 3WUT chain H against the predicted model Q53EZ4: TM-score 0.90, RMSD 0.80 Å
Elsewhere
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