UniProt Q4WPS9
CaaX farnesyltransferase beta subunit Ram1 (Q4WPS9)
CaaX farnesyltransferase beta subunit Ram1 (UniProt Q4WPS9), EC 2.5.1.58: 8 experimental structures on GenesisL1, 7 ligands bound, 33 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q4WPS9
- Protein
- CaaX farnesyltransferase beta subunit Ram1
- EC
- 2.5.1.58
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 33 · 4 records with a druggable one
Structures
8 records of Q4WPS9 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4L9P | Crystal structure of Aspergillus fumigatus protein farnesyltransferase complexed with the FII… | x-ray diffraction | B | ZN, CL, FII | 8 (best 0.80) |
| 4L9P | Crystal structure of aspergillus fumigatus protein farnesyltransferase complexed with the fii… | x-ray diffraction | B | — | — |
| 4LNB | Aspergillus fumigatus protein farnesyltransferase ternary complex with farnesyldiphosphate and… | x-ray diffraction | B | FPP, ZN, ED5 | 9 (best 0.81) |
| 4LNB | Aspergillus fumigatus protein farnesyltransferase ternary complex with farnesyldiphosphate and… | x-ray diffraction | B | — | — |
| 4LNG | Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib | x-ray diffraction | B | ZN, JAN, FPP, K | 8 (best 0.79) |
| 4LNG | Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib | x-ray diffraction | B | — | — |
| 4MBG | Crystal structure of Aspergillus fumigatus protein farnesyltransferase binary complex with… | x-ray diffraction | B | FPP, ZN, K | 8 (best 0.80) |
| 4MBG | Crystal structure of aspergillus fumigatus protein farnesyltransferase binary complex with… | x-ray diffraction | B | — | — |
Ligands
- ZN · Zinc ion · in 4 records
- FPP · Farnesyl diphosphate · in 3 records
- K · Potassium ion · in 2 records
- CL · Chloride ion · in 1 record
- ED5 · tert-butyl 4-({(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)[(2-methylphenyl)sulfonyl]amino}methyl)piperidine-1-carboxylate · in 1 record
- FII · [(3,7,11-trimethyl-dodeca-2,6,10-trienyloxycarbamoyl)-methyl]-phosphonic acid · in 1 record
- JAN · 6-[(S)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one · in 1 record
Elsewhere
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