UniProt Q4WL81
Conidial surface nicotinamide adenine dinucleotide glycohydrolase nadA (Q4WL81)
Conidial surface nicotinamide adenine dinucleotide glycohydrolase nadA (UniProt Q4WL81), EC 3.2.2.-, 3.2.2.5: 9 experimental structures on GenesisL1, 11 ligands bound, 47 pockets. Binding sites, pockets, druggability and 3D…
- UniProt
- Q4WL81
- Protein
- Conidial surface nicotinamide adenine dinucleotide glycohydrolase nadA
- EC
- 3.2.2.-, 3.2.2.5
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 47 · 6 records with a druggable one
Structures
9 records of Q4WL81 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6YGE | NADase from Aspergillus fumigatus | x-ray diffraction | B, A | NAG, FUC, CA | 8 (best 0.60) |
| 6YGE | Nadase from aspergillus fumigatus | x-ray diffraction | B, A | NAG, FUC, CA | — |
| 6YGF | NADase from Aspergillus fumigatus with trapped reaction products | x-ray diffraction | B, A | NAG, FUC, PO4, NCA, AR6 | 8 (best 0.59) |
| 6YGF | Nadase from aspergillus fumigatus with trapped reaction products | x-ray diffraction | B, A | NAG, FUC, PO4, NCA, AR6 | — |
| 6YGG | NADase from Aspergillus fumigatus complexed with a substrate anologue | x-ray diffraction | A, B | NAG, FUC, CA, NA, DQV | 7 (best 0.59) |
| 6YGG | Nadase from aspergillus fumigatus complexed with a substrate anologue | x-ray diffraction | A, B | NAG, FUC, CA, NA, DQV | — |
| 8PMR | NADase from Aspergillus fumigatus with mutated calcium binding motif (D219A/E220A) | x-ray diffraction | A, B, C, D | NAG, FUC, MAN | 12 (best 0.68) |
| 8PMS | NADase from Aspergillus fumigatus with replaced C-terminus from Neurospora crassa | x-ray diffraction | A, B, C, D | NAG, FUC, BMA, MAN, AKR | 9 (best 0.77) |
| 8R17 | Crystal structure of Neurospora crassa NADase with modified C-terminus | x-ray diffraction | A | NAG | 3 (best 0.61) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 9 records
- FUC · alpha-L-fucopyranose · in 8 records
- CA · Calcium ion · in 4 records
- AR6 · [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate · in 2 records
- DQV · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3S,4R,5S)-5-(3-carbamoylphenyl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name) · in 2 records
- MAN · alpha-D-mannopyranose · in 2 records
- NA · Sodium ion · in 2 records
- NCA · Nicotinamide · in 2 records
- PO4 · Phosphate ion · in 2 records
- AKR · Acrylic acid · in 1 record
- BMA · beta-D-mannopyranose · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.