UniProt Q46079
Chondroitinase B (Q46079)
Chondroitinase B (UniProt Q46079), EC 4.2.2.4: 4 experimental structures and 1 predicted model on GenesisL1, 8 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q46079
- Protein
- Chondroitinase B
- EC
- 4.2.2.4
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 8
- Pockets
- 8 · 0 records with a druggable one
Structures
5 records of Q46079 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OFL | Crystal structure of chondroitinase B complexed to dermatan sulfate hexasaccharide | x-ray diffraction | A | MAN, GCU, RAM, ASG, GCD, NGK | 5 (best 0.47) |
| 1OFL | Crystal structure of chondroitinase B complexed to dermatan sulfate hexasaccharide | x-ray diffraction | A | — | — |
| 1OFM | Crystal structure of chondroitinase B complexed to chondroitin 4-sulfate tetrasaccharide | x-ray diffraction | A | MAN, GCU, RAM, ASG, BDP | 3 (best 0.50) |
| 1OFM | Crystal structure of chondroitinase B complexed to chondroitin 4- sulfate tetrasaccharide | x-ray diffraction | A | — | — |
| Q46079 | AlphaFold monomer V2.0 prediction for chondroitinase-B (Q46079) | predicted | A | — | — |
Ligands
- ASG · 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose · in 2 records
- GCU · alpha-D-glucopyranuronic acid · in 2 records
- MAN · alpha-D-mannopyranose · in 2 records
- RAM · alpha-L-rhamnopyranose · in 2 records
- BDP · beta-D-glucopyranuronic acid · in 1 record
- CA · Calcium ion · in 1 record
- GCD · 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid · in 1 record
- NGK · 2-acetamido-2-deoxy-4-O-sulfo-alpha-D-galactopyranose · in 1 record
Experiment against prediction
- 1OFM chain A against the predicted model Q46079: TM-score 1.00, RMSD 0.17 Å
- 1OFM chain A against the predicted model Q46079: TM-score 1.00, RMSD 0.17 Å
- 1OFL chain A against the predicted model Q46079: TM-score 1.00, RMSD 0.18 Å
- 1OFL chain A against the predicted model Q46079: TM-score 1.00, RMSD 0.18 Å
Elsewhere
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