UniProt Q3T112
Proteasome subunit beta type-8 (Q3T112)
Proteasome subunit beta type-8 (UniProt Q3T112), EC 3.4.25.1: 6 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q3T112
- Protein
- Proteasome subunit beta type-8
- EC
- 3.4.25.1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 15 · 3 records with a druggable one
Structures
7 records of Q3T112 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28alpha-beta in complex with immunoproteasome | electron microscopy | Y, 2 | — | 2 (best 0.76) |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | Y, 2 | — | — |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | Y, 2 | — | 6 (best 0.75) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | Y, 2 | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | Y, 2 | — | 3 (best 0.80) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | Y, 2 | — | — |
| Q3T112 | AlphaFold monomer V2.0 prediction for proteasome subunit beta type-8 (Q3T112) | predicted | A | — | 4 (best 0.46) |
Experiment against prediction
- 7DR7 chain Y against the predicted model Q3T112: TM-score 0.98, RMSD 0.74 Å
- 7DR7 chain Y against the predicted model Q3T112: TM-score 0.98, RMSD 0.74 Å
- 7DR7 chain 2 against the predicted model Q3T112: TM-score 0.98, RMSD 0.74 Å
- 7DRW chain Y against the predicted model Q3T112: TM-score 0.98, RMSD 0.77 Å
- 7DRW chain Y against the predicted model Q3T112: TM-score 0.98, RMSD 0.77 Å
- 7DRW chain 2 against the predicted model Q3T112: TM-score 0.98, RMSD 0.77 Å
- 7DR6 chain Y against the predicted model Q3T112: TM-score 0.97, RMSD 0.89 Å
- 7DR6 chain Y against the predicted model Q3T112: TM-score 0.97, RMSD 0.89 Å
- 7DR6 chain 2 against the predicted model Q3T112: TM-score 0.97, RMSD 0.91 Å
Elsewhere
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