UniProt Q3T108
Proteasome subunit beta type-4 (Q3T108)
Proteasome subunit beta type-4 (UniProt Q3T108), EC 3.4.25.1: 9 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q3T108
- Protein
- Proteasome subunit beta type-4
- EC
- 3.4.25.1
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 26 · 6 records with a druggable one
Structures
10 records of Q3T108 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28alpha-beta in complex with immunoproteasome | electron microscopy | K, V | — | 3 (best 0.76) |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | K, V | — | — |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | K, V | — | 6 (best 0.76) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | K, V | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | n, V | — | 2 (best 0.78) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | n, V | — | — |
| 8AZK | Bovine 20S proteasome, untreated | electron microscopy | N, 2 | — | 4 (best 0.76) |
| 8FZ5 | The PI31-free Bovine 20S proteasome | electron microscopy | N, b | — | 3 (best 0.74) |
| 8FZ6 | The human PI31 complexed with bovine 20S proteasome | electron microscopy | N, b | — | 7 (best 0.75) |
| Q3T108 | AlphaFold monomer V2.0 prediction for proteasome subunit beta type-4 (Q3T108) | predicted | A | — | 1 (best 0.24) |
Experiment against prediction
- 8FZ5 chain N against the predicted model Q3T108: TM-score 0.99, RMSD 0.57 Å
- 8FZ5 chain b against the predicted model Q3T108: TM-score 0.99, RMSD 0.57 Å
- 8FZ6 chain N against the predicted model Q3T108: TM-score 0.99, RMSD 0.57 Å
- 7DR7 chain K against the predicted model Q3T108: TM-score 0.98, RMSD 0.88 Å
- 7DR7 chain K against the predicted model Q3T108: TM-score 0.98, RMSD 0.88 Å
- 8AZK chain N against the predicted model Q3T108: TM-score 0.98, RMSD 0.84 Å
- 7DR7 chain V against the predicted model Q3T108: TM-score 0.97, RMSD 1.12 Å
- 7DR7 chain V against the predicted model Q3T108: TM-score 0.97, RMSD 1.12 Å
- 8AZK chain 2 against the predicted model Q3T108: TM-score 0.97, RMSD 0.94 Å
- 7DRW chain n against the predicted model Q3T108: TM-score 0.97, RMSD 1.05 Å
Elsewhere
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