UniProt Q3T0Y5
Proteasome subunit alpha type-2 (Q3T0Y5)
Proteasome subunit alpha type-2 (UniProt Q3T0Y5): 9 experimental structures and 1 predicted model on GenesisL1, 46 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q3T0Y5
- Protein
- Proteasome subunit alpha type-2
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 46 · 6 records with a druggable one
Structures
10 records of Q3T0Y5 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28alpha-beta in complex with immunoproteasome | electron microscopy | M, f | — | 8 (best 0.84) |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | M, f | — | — |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | F, M | — | 7 (best 0.81) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | F, M | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | B, h | — | 10 (best 0.86) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | B, h | — | — |
| 8AZK | Bovine 20S proteasome, untreated | electron microscopy | B, P | — | 6 (best 0.79) |
| 8FZ5 | The PI31-free Bovine 20S proteasome | electron microscopy | B, P | — | 9 (best 0.80) |
| 8FZ6 | The human PI31 complexed with bovine 20S proteasome | electron microscopy | B, P | — | 4 (best 0.80) |
| Q3T0Y5 | AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-2 (Q3T0Y5) | predicted | A | — | 2 (best 0.43) |
Experiment against prediction
- 7DR6 chain M against the predicted model Q3T0Y5: TM-score 0.96, RMSD 1.26 Å
- 7DR6 chain M against the predicted model Q3T0Y5: TM-score 0.96, RMSD 1.26 Å
- 7DRW chain B against the predicted model Q3T0Y5: TM-score 0.96, RMSD 1.33 Å
- 7DRW chain B against the predicted model Q3T0Y5: TM-score 0.96, RMSD 1.33 Å
- 7DR7 chain M against the predicted model Q3T0Y5: TM-score 0.95, RMSD 1.22 Å
- 7DR7 chain M against the predicted model Q3T0Y5: TM-score 0.95, RMSD 1.22 Å
- 7DRW chain h against the predicted model Q3T0Y5: TM-score 0.95, RMSD 1.56 Å
- 7DRW chain h against the predicted model Q3T0Y5: TM-score 0.95, RMSD 1.56 Å
- 8FZ5 chain B against the predicted model Q3T0Y5: TM-score 0.95, RMSD 1.08 Å
- 8FZ6 chain B against the predicted model Q3T0Y5: TM-score 0.95, RMSD 1.09 Å
Elsewhere
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