UniProt Q381A3
Intraflagellar transport protein 22 (Q381A3)
Intraflagellar transport protein 22 (UniProt Q381A3): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q381A3
- Protein
- Intraflagellar transport protein 22
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 2 records with a druggable one
Structures
5 records of Q381A3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6IA7 | T. brucei IFT22 GTP-bound crystal structure | x-ray diffraction | A, B | GTP, MG, CA | 2 (best 0.75) |
| 6IA7 | T. brucei IFT22 GTP-bound crystal structure | x-ray diffraction | A, B | GTP, MG, CA | — |
| 6IAE | T. brucei IFT22 GDP-bound crystal structure | x-ray diffraction | A, B | GTP, MG | 1 (best 0.71) |
| 6IAE | T. brucei IFT22 GDP-bound crystal structure | x-ray diffraction | A, B | GTP, MG | — |
| Q381A3 | AlphaFold monomer V2.0 prediction for intraflagellar transport protein 22 (Q381A3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6IA7 chain A against the predicted model Q381A3: TM-score 0.93, RMSD 1.58 Å
- 6IA7 chain A against the predicted model Q381A3: TM-score 0.93, RMSD 1.58 Å
- 6IAE chain A against the predicted model Q381A3: TM-score 0.92, RMSD 1.66 Å
- 6IAE chain A against the predicted model Q381A3: TM-score 0.92, RMSD 1.66 Å
- 6IAE chain B against the predicted model Q381A3: TM-score 0.92, RMSD 1.78 Å
- 6IAE chain B against the predicted model Q381A3: TM-score 0.92, RMSD 1.78 Å
- 6IA7 chain B against the predicted model Q381A3: TM-score 0.91, RMSD 1.90 Å
- 6IA7 chain B against the predicted model Q381A3: TM-score 0.91, RMSD 1.90 Å
Elsewhere
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