UniProt Q32KN8
Tubulin alpha-3 chain (Q32KN8)
Tubulin alpha-3 chain (UniProt Q32KN8), EC 3.6.5.-: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q32KN8
- Protein
- Tubulin alpha-3 chain
- EC
- 3.6.5.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 31 · 3 records with a druggable one
Structures
3 records of Q32KN8 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8OTZ | 48-nm repeat of the native axonemal doublet microtubule from bovine sperm | electron microscopy | AA, AC, AE, AG, AI, AK, AM, BA, BC, BE, BG, BI, BK, BM, CA, CC, CE, CG, CI, CK, CM, DA, DC, DE, DG, DI, DK, DM, EC, EE, EG, EI, EK, EM, FC, FE, FG, FI, FK, FM, GC, GE, GG, GI, GK, GM, HC, HE, HG, HI, HK, HM, HO, IC, IE, IG, II, IK, IM, IO, JC, JE, JG, JI, JK, JM, KC, KE, KG, KI, KK, KM, KO, LC, LE, LG, LI, LK, LM, MC, ME, MG, MI, MK, MM, NA, NC, NE, NG, NI, NK, OA, OC, OE, OG, OI, OK, PA, PC, PE, PG, PI, PK, PM, QA, QC, QE, QG, QI, QK, QM, RA, RC, RE, RG, RI, RK, RM, SA, SC, SE, SG, SI, SK, SM, TC, TE, TG, TI, TK, TM, UC, UE, UG, UI, UK, UM, VC, VE, VG, VI, VK, VM, WC, WE, WG, WI, WK, WM | GTP, MG, GDP | 19 (best 0.88) |
| 8OU0 | bovine sperm endpiece singlet microtubules (one tubulin dimer and associated microtubule inner… | electron microscopy | A | GTP, MG | 9 (best 0.84) |
| Q32KN8 | AlphaFold monomer V2.0 prediction for tubulin alpha-3 chain (Q32KN8) | predicted | A | — | 3 (best 0.61) |
Ligands
Experiment against prediction
- 8OTZ chain JC against the predicted model Q32KN8: TM-score 0.99, RMSD 0.91 Å
- 8OTZ chain MG against the predicted model Q32KN8: TM-score 0.99, RMSD 0.89 Å
- 8OTZ chain BI against the predicted model Q32KN8: TM-score 0.99, RMSD 0.91 Å
- 8OTZ chain MI against the predicted model Q32KN8: TM-score 0.99, RMSD 0.91 Å
- 8OTZ chain KG against the predicted model Q32KN8: TM-score 0.99, RMSD 0.92 Å
- 8OTZ chain HI against the predicted model Q32KN8: TM-score 0.98, RMSD 0.93 Å
- 8OTZ chain OK against the predicted model Q32KN8: TM-score 0.98, RMSD 0.96 Å
- 8OTZ chain KO against the predicted model Q32KN8: TM-score 0.98, RMSD 0.95 Å
- 8OTZ chain BE against the predicted model Q32KN8: TM-score 0.98, RMSD 0.97 Å
- 8OTZ chain KC against the predicted model Q32KN8: TM-score 0.98, RMSD 0.99 Å
Elsewhere
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