UniProt Q2YDE4
Proteasome subunit alpha type-6 (Q2YDE4)
Proteasome subunit alpha type-6 (UniProt Q2YDE4): 9 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2YDE4
- Protein
- Proteasome subunit alpha type-6
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 29 · 6 records with a druggable one
Structures
10 records of Q2YDE4 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DR6 | PA28alpha-beta in complex with immunoproteasome | electron microscopy | L, e | — | 6 (best 0.84) |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | L, e | — | — |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | E, L | — | 4 (best 0.76) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | E, L | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | A, f | — | 6 (best 0.86) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | A, f | — | — |
| 8AZK | Bovine 20S proteasome, untreated | electron microscopy | A, O | — | 4 (best 0.78) |
| 8FZ5 | The PI31-free Bovine 20S proteasome | electron microscopy | A, O | — | 5 (best 0.77) |
| 8FZ6 | The human PI31 complexed with bovine 20S proteasome | electron microscopy | A, O | — | 3 (best 0.78) |
| Q2YDE4 | AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-6 (Q2YDE4) | predicted | A | — | 1 (best 0.32) |
Experiment against prediction
- 8FZ5 chain A against the predicted model Q2YDE4: TM-score 0.99, RMSD 0.64 Å
- 8FZ6 chain A against the predicted model Q2YDE4: TM-score 0.99, RMSD 0.68 Å
- 7DR7 chain L against the predicted model Q2YDE4: TM-score 0.98, RMSD 0.94 Å
- 7DR7 chain L against the predicted model Q2YDE4: TM-score 0.98, RMSD 0.94 Å
- 8AZK chain A against the predicted model Q2YDE4: TM-score 0.98, RMSD 0.91 Å
- 7DR7 chain E against the predicted model Q2YDE4: TM-score 0.98, RMSD 0.97 Å
- 7DR7 chain E against the predicted model Q2YDE4: TM-score 0.98, RMSD 0.97 Å
- 7DRW chain A against the predicted model Q2YDE4: TM-score 0.97, RMSD 0.95 Å
- 7DRW chain A against the predicted model Q2YDE4: TM-score 0.97, RMSD 0.95 Å
- 8AZK chain O against the predicted model Q2YDE4: TM-score 0.97, RMSD 0.96 Å
Elsewhere
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